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Intravenous ketamine infusion will result in analgesia
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1. The effect of a single oral dose of L-000830982 versus oral placebo and an intravenous infusion of ethanol versus placebo on tremor over a 8-hour period in men and women with essential tremor will be estimated; 2. The sensitivity and specificity…
S(+)-ketamine reduces pain in patients with Complex Regional Pain Syndome type 1 having symptoms shorter than 6 months and longer than 3 years.
1. Does Levothyroxine treatment for subclinical hypothyroidism give multi-modal benefits for the oldest old people with subclinical hypothyroidism? 2. Are benefits seen across a wide range of outcomes, including prevention of cardiovascular disease…
Inhibition of the H1 receptor will lead to an improvement of rectal sensitivity, followed by less abdominal symptoms in patients with irritable bowel syndrome.
In EPF, the sequential combination of mifepristone with misoprostol is superior to the use of misoprostol alone in terms of complete evacuation of products of conception, patient satisfaction, complications, side effects and costs.
To assess the impact of the physical form of five different cocoa matrices on the bioavailability of the monomeric flavan-3-ols.
Treatment with Botox will give a better healing rate for anal fissures compared to treatment with isosorbidedinitrate ointment.
1.We expect participants in the experimental condition to show a reduced gmbling behaviour 2. We expect participants in the experimental condition to show a decrease in approach bias towards gambling cues, and weaker approach implicit associations…
Our hypothesis is that critical ill COVID-19 patients suffer more from their own immune response against the virus, than from the viral infection itself. Alkaline phosphatase (RESCAP®) has proven to reduce SIRS reactions by neutralizing the…
Rationale: There is increasing evidence that Nicotine Replacement Therapy (NRT) may help adolescents to successfully quit smoking. However data on the effectiveness and safety of NRT among adolescents are limited and a large clinical trial of…
Motor cortex or cerebellar tDCS(transcranial Direct Current Stimulation) will enhance motor skill learning in heatlhy subjects and chronic stroke survivors. Stimulating the motor cortex will result in an increase in offline learning, whereas…
We hypothesize that both nitrate and sucrose will reduce GI damage and improve GI blood flow during high-intensity exercise compared with placebo.
Hypertension can be prevented, or substantially delayed, by a temporary and early anti-hypertensive intervention with an ACE inhibitor in persons at high risk for future hypertension and hypertension related complications.
We hypothesize that the use of a GnRH-antagonist in cycles with Mild Ovarian Hyperstimulation (MOH) combined with Intrauterine insemination (IUI) programs significantly improves live birth rates compared with MOH and a placebo.
Chronic chilblains is a common disease causing major restrictions in daily life, nevertheless little is known about treatment. In a literature search, we found thin evidence of three interventions: fluocinolone cream, nifedipine and vitamin D3.…
The addition of PEMF to cast immobilisation in fresh scaphoid fractures will accelerate consolidation both clinically and radiologically. Possibly the incidence of non-union will be reduced.
High dose statins will reduce atherosclerosis in post-coarctectomy patients.
The addition of milk protein hydrolysate and tryptophan rich proteins and/or decreasing stomach emptying rate in combination with increased satiety, will improve sleep onset and efficiency significantly as compared with the current available growing…