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Single dose intranasal dexmedetomidine can be administered safely to elderly people as premedication with respects to hemodynamic changes, irrespective of the concurrent use of betablocking medication
The objective of this prospective randomised, double-blind, controlled trial is to evaluate the effect of OPEP use on respiratory symptoms in patients with COPD or chronic bronchitis with excessive mucus in daily clinical practice.
the active treatment group has an improvement of at least 10 points of DASH functional outcome more than the placebo group.
Oral sodium butyrate use in subjects with type 1 diabetes will lead to an altered innate immune system response, ultimately improving beta cell function and glucose regulation.
we hypothesize that translocation of Gram- negative intestinal bacteria is associated with changes in (small) intestinal microbiota composition and can be influenced by fecal microbiota transplantation.
1. Methylphenidate (MPH) increases activation in task relevant areas and task performance 2. Hydrocortisone (HC) increases activation in task relevant areas and task performance 3. MPH + HC increase activation in task relevant areas, but might…
It is hypothesized that an intervention with the KPR could decrease pelvic tilt, as measured using clinical leg length difference and the ASIS-PSIS angle, for 50% or create a crest height difference smaller than 0.5 centimeters in patients with non…
There are no differences in clinical treatment outcome between mechanical debridement alone or mechanical debridement along with use of Delmopinol for a time period of 3 months in treating peri-implant mucositis.
Breast cancer patients with chronic pain at the breast region will have a greater decrease in pain after a botulinum toxin infiltration, an individual physical therapy programme and home exercise programme than patients who reveive a saline solution…
We perform this randomized trial to test the hypothesis that a combination of paracervical anesthesia and fundal anesthesia is not superior to paracervical anesthesia only.
Protein supplementation will augment the training induced gains in skeletal muscle mass and strength.
The aim of this research project is to investigate cannabidiol as a new medicine to target the cannabinoid system in the reduction of anxiety disorder symptoms. The research question is whether cannabidiol, as an augmentation strategy of exposure…
Modulation of phosphate intake can affect the antiproteinuric efficacy of RAAS-blockade therapy in CKD patients
Bezafibrate will significantly reduce post-prandial non-HDL cholesterol in patients with Familial Dysbetalipoproteinemia compared to placebo.
The objective is to investigate the effect of cannabidiol (synthetic) as compared to placebo in facilitating fear extinction and reducing fear retention and reinstatement.
Lanreotide therapy can stabilize or reduce tumor size in Gallium-68 DOTATATE positive pituitary NFMA
Hypothesis 1: Participants who receive either of two CBM interventions will reduce their gambling more than participants completing the placebo intervention immediately after the re-training (post-intervention assessment) and by the 3-and 6-month…
Intravenously administred ascorbic acid improves reduction in wound area of a vascular surgical wound of at least 30% within 4 weeks post-surgery.