39 resultaten
We hypothesize that probiotics with vitamin K2 producing properties can improve vitamin K status, which will eventually reduce the risk of coronary calcification.
We hypothesize that GABA could improve glucose tolerance and cardiovascular health after long-term supplementation
The main objective is to evaluate the efficacy and safety of phenytoin cream in patients with neuropathic pain due to CIAP
The pericapsular nerve group (PENG) block is superior to placebo 'sham' blocks in hip arthroplasty surgery in reducing patients pain scores (Numeric Rating Scale of 0 to 10), on the day of surgery
We expect that metformin in combination with lifestyle interventions reduces Antipsychotic induced Weight Gain compared to placebo in combination with lifestyle interventions.
We hypothesize that methylphenidate improves ADHD manifestations in children and adults with SMS.
This study hypothesizes that doxapram will protect preterm infants from both invasive ventilation (and related lung disease) and apnea of prematurity related hypoxia (and related impaired brain development).
combining a standard DIEP-flap breast reconstruction (BR) with an inguinal lymph node transplant will lead to an improvement of the BCR
We expect an incidence of delirium in our control group of 30%. This is based on literature documenting incidence of delirium in neurosurgical patients in a northern European population of 29-33%. The expected effect cannot be based on previous…
Our hypothesis is that critical ill COVID-19 patients suffer more from their own immune response against the virus, than from the viral infection itself. Alkaline phosphatase (RESCAP®) has proven to reduce SIRS reactions by neutralizing the…
We hypothesize that long-term continuation of macrolide maintenance therapy after at least 1 year of treatment in COPD patients results in a prolonged time to next exacerbation compared to withdrawal of azithromycin macrolide treatment
We hypothesize that our integrated care intervention, as compared to usual care and a placebo version of the m/eHealth intervention, will increase quality of life of KA patients by improving societal participation including work, indirectly reducing…
Oral bisphosphonate supplementation or the MMR vaccine can be used as immune potentiators when simultaneously administered with BCG, to further amplify the BCG-induced trained immunity response and maximize potential protective effects against COVID…
Sacroiliac joint infiltration with bupivacaine 0.25% is superior to placebo in reducing post-operative pain.
BCG vaccination may induce (partial) protection against susceptibility to and/or severity of SARS-CoV-2 infection. This will lead to reduced workplace absenteism under health care workers taking care of patients with COVID-19
Our hypothesis is that growth hormone threatment in adults with Prader-Willi Syndrome will improve their metabolic and cardiovascuar health, thereby resulting in a reduced mortality.
CONFIRMATORY HYPOTHESIS Our novel cognitive training incorporates several aspects that are expected to increase its effectiveness when compared to traditional Cognitive Bias Modification (CBM). As a confirmatory hypothesis we expect that, as an add-…
We hypothesize that our individual rehabilitation program will be (cost-)effective regarding the primary and secondary health- and work-related outcome measures of work in cancer survivors with an employment contract, compared to care as usual.…
Metformin combined with doxycycline will result in a better improvement in HS severity and the pre-diabetic condition of the patients compared to doxycycline monotherapy.