116 resultaten
Paravertebral analgesia is associated with superior quality of recovery by achieving comparable pain control whilst having less side-effects.
The pharmacokinetics of erlotinib 150mg QD is comparable to the pharmacokinetics erlotinib 75mg + ritonavir 200mg QD.
An intervention aimed at improving recovery during work will lead to less fatigue in shiftwork employees.
We expect to see improved white matter integrity (i.e. estimated by increased fractional anisotropy, decreased mean diffusivity) in response to Tecfidera treatment. As a result physical functioning might improve, cognitive functioning will be stable…
The YEARS algorithm is non-inferior to management by CTPA with regard to 3-month recurrent VTE rates and will reduce the rate of unnecessary CTPA in patients with clinically suspected PE and active malignancy.
A switch to thrombininhibitor dabigatran or addition of tranexamic acid to the factor Xa inhibitor may be effective in women who experience heavy menstrual bleeding during anticoagulant treatment with factor Xa inhibitors.
We hypothesize that the extended antibiotic prophylactic regimen is associated with increased infection-free survival of the implant within one year after revision arthroplasty (index revision arthroplasty) compared to a single dose.
Our hypothesis is that; 1) the information video contributes to an improved understanding of the lumbar puncture procedure, and 2) reduces anxiety for the procedure.
The present study will assess the composition of the oral microbiome in patients who have been referred to the NKCV (Nederlands Kenniscentrum Chronische Vermoeidheid) for treatment for complaints of severe and protracted fatigue. Objective…
The sugammadex dose required to achieve a TOF-ratio of 1 is not known when monitoring is not used. Administration of sugammadex based on the rocuronium dosage, while aiming for complete recovery, should reduce the risk of residual NMB.
EBUS/EUS-B sampling of mediastinal/hilar lymph nodes and/or primary lung tumors with the Acquireᵗᵐ 22G TBNB needle has a higher suitability rate for the assessment of PD-L1 expression in comparison to the regular 22G TBNA needle in patients with…
Providing an optimal start for vulnerable mother and child dyads during the early postpartum period.
Reduced amount of low empowerment scores postpartum among the intervention group, achieved by an eHealth application to support vulnerable mother and child dyads.
Both interventions (GRAIL training & endurance and strength training (control intervention)) will result in an increase in gait speed, functional walking ability and social participation. However, the GRAIL training will result in larger…
After absorption tamoxifen is metabolized by CYP3A4 and CYP2D6 in several (active) metabolites of which endoxifen is the most important.(11) Tamoxifen, like many anti-cancer drugs, relies on phase II metabolism before they can be excreted from the…
Currently there is little knowledge about the effectiveness of (biopsychosocial) interventions and the cost-effectiveness of adherence to orthopaedic shoes has not been studied at all. Therefore the aim of the current study is to assess the (cost…
OR workflow for surgeons needing to interact with the laparoscopic equipment during surgery is optimized using TedCube© in combination with the Myo™ gesture control armband and/or a wireless headset.
Trifluridine is primarily metabolized through degradation by thymidine phosphorylase to the inactive metabolite 5-(trifluoromethyl)-uracil (FTY) without any involvement of the cytochrome P450 enzyme system. The primary route of excretion of…
Awake craniotomy improves safety and efficacy during surgery for glioblastoma in eloquent areas
Individual-directed resilience training can reduce chronic stress and prevent burnout among students
Based on most recent insights in AAV treatment, the present study intends to evaluate whether combining rituximab with cyclophosphamide is superior to current standard of care with rituximab only to induce a favorable immunological state of MRA in…