314 resultaten
The main outcome is the identification of clinical, biochemical, and genetic factors associated with resilience to cognitive decline in extreme elderly subjects. At baseline we will test the association between cognitive resilience and amyloid…
We expect higher participant scores for self-efficacy, behavioral intentions and evaluation for the photo story intervention compared to a comparable traditional brochure. We expect that the majoritiy of participants prefers the photo story…
Carcinoembryonic antigen (CEA) is used as a biomarker in colon carcinoma, however in patients with (non-)small cell lung cancer ((N)SCLC) increased serum CEA levels commonly found. Since decline of high CEA levels in colon carcinoma is predictive…
The introduction of biopharmaceuticals (BP) has been a critical step forward in care for RA and 10 BP are now licensed for the treatment of RA. In spite of this progress, failure of response to BP is frequent and in most of the registries, less than…
To characterize the effect of Aubagio on the Cognitive status, measured by the Brief Repeatable Battery – neuropsychological (BRB-N battery) in RRMS patients
Ultrasound guided reduction of dorsally angulated distal radius fractures will reduce the amount of attemps necessary to achieve an acceptable result compared to the standard blind procedure
H0: The effect of at least one of the gum-thickened viscosities is equal to the effect using thin liquid, with respect to the safety of swallowing in patients with chronic post stroke oropharyngeal dysphagia. H1: The effect of using gum-thickened…
We hypothesize that a single night of short sleep duration (4 hours), compared to normal sleep duration (8 hours) reduces metabolic flexibility, increases insulin resistance and thereby reduces HPA-reactivity. Furthermore, we hypothesize that a…
4 week n-3 PUFA supplementation will enhance daily muscle protein synthesis rates in older men on a standardized diet.
We hypothesize that age-related changes in hepatic and intestinal drug metabolism affect the pharmacokinetics of midazolam.
The newer BladderScan PRIME with real time echo images (= pre-scan) is more accurate in measuring bladder volumes than measuring bladder volume without pre-scan or than the older version of the BladdderScan; the BVI 9400. and
In severe heart failure, the heart¡¯s pumping power is weak, leading to fluid retention and hospital admission of the affected patient. This project will investigate if a temporary pump (intra-aortic balloon pump, IABP) in the aorta will treat fluid…
Family Integrated Care in Single Family Rooms improves neurodevelopmental outcome in preterm infants
Numbers of hip and knee arthroplasties are increasing worldwide. The optimization of the treatment and the scientifically supported procedures are implemented in clinical pathways (CPs). CPs have developed during the past decades and this systematic…
Implementation of complex interventions could be improved by acknowledging the local (nursing home) problems in the care process. The implementation of a facility tailored intervention will lead to a decrease in psychotropic drug use throughout the…
Measuring anti-Xa levels 4 hours after the first tinzaparin gift leads to faster achieving of adequate anti-Xa levels with fewer dose adjustments
Surgical treatment (DAIR on day 10) will result in a 50% reduction rate of revision for PJI up to one year after primary TKA/THA compared to nonsurgical treatment. Consequently surgical treatment is more (cost) effective compared to nonsurgical…