498 resultaten
The purpose of this study is to evaluate the efficacy of oral ibandronate (versus placebo) added to the standard radiotherapy regimen for painful bone metastases to reduce pain, to reduce the need of analgesics, and to reduce skeletal-related events…
The hypothesis is that cummulative doses of 2.5, 5.0 or 7.5 gram methylprednisolone infusions are equally effective in moderately severe Graves' ophthalmopathy, but that the doses differ in the number and severity of side effects.
We hypothesize that a treatment algorithm that is based on a simple validated measure of health status (CCQ) improves quality of life (as measured on a separate scale) and other classical COPD outcome measurement parameters such as exacerbation…
Adding amantadine to the standard anti-HCV treatment can improve sustained response rates in chronic hepatitis C.
Nebulised DNase has a decreasing effect on the duration of a hospital admission in infants admitted with an RSV-bronchiolitis.
N/A
If the 'level of fitness dependant protocol' produces a higher VO2-max in comparison with the adapted Bruce protocol, then a relevant difference can be shown when the results are statistically analysed.
Prolonged antibiotic treatment of patients diagnosed with presumed PLD (as endorsed by the international ILADS guidelines) leads to better patient outcome than short-term treatment as endorsed by the Dutch CBO guidelines.
The use of by filtration-leukocyte reduced blood transfusions in patients undergoing cardiac surgery, will result in lower alloimmunization frequencies compared to using buffy-coat depleted blood transfusions. This has previously been shown in…
N/A
1. The effect of a single oral dose of L-000830982 versus oral placebo and an intravenous infusion of ethanol versus placebo on tremor over a 8-hour period in men and women with essential tremor will be estimated; 2. The sensitivity and specificity…
S(+)-ketamine reduces pain in patients with Complex Regional Pain Syndome type 1 having symptoms shorter than 6 months and longer than 3 years.
The TENLEP Trials proposal builds on the findings of the INFIR Cohort Study and the recommendations of the NLR-funded international Workshop on Neuropathology in Leprosy in the Netherlands in 2007. At this workshop, several key research questions…
Based on its general pro-hemostatic potential, prothrombin complex concentrate may be effective in (completely or partially) reversing the anticoagulant effect of the new antithrombotic agents Dabigatran and Rivaroxaban.
Antibiotic treatment of hospitalised children with RSV LRTD has no beneficial effect on the clinical course.
Local injection therapy with 1ml of triamcinolonacetonide (10mg/ml) provided by a primary care physician is more effective than injection with 1ml NaCl (0,9%) for trigger finger, de Quervain's tenosynovitis and carpal tunnel syndrome.
In the present study we will investigate the pharmacokinetic profile of three doses of sublingual testosterone, and measure subjective and physiological measures of sexual functioning in healty premenopausal women. The lowest effective dose of…
A preoperative subconjunctival injection of Dexamethason reduces the incidence of proliferative vitreoretinopathy in patients with ablatio retinae.
To determine whether doubling the dose of corticosteroid injections in the treatment of arthritis in knee joints is more effective, both in number of responding patients and in duration of response (pain relief).