82 resultaten
A combination therapy of bladder training with PTNS(Posterior Tibial Nerve Stimulation) has a synergistic effect in comparison with bladder training alone in the treatment of over active bladder.
The healing of donor site wounds after split-skin grafting can be promoted by the use of one of five specific wound dressing materials as compared in this trial.
Activation of SIRT1 (silent information regulator transcript) results in inhibition of inflammation in humans.
The effect of stepping down asthma therapy in clinically stable children on exercise induced asthma.
We hypothesized that in a subgroup of patients EIBH would improve after the cessation of LABA.
Hearing aid fitting will reduce the tinnitus burden in patients with mild hearing loss.
We hypoothesize that the effect that a single dose of montelukast has on exercise induced bronchoconstriction correlates with the effect it has after 8 weeks of treatment.
Presence of postural instability and gait dissorder PIGD (gait disorders, balance impairment, falls, fal-related injuries and FOG) are an important and disabling feature of idiopathic Parkinson’s disease (PD) where the level of functional ability is…
By using a surgical safety checklist, the incidence of postoperative complications will decrease.
The behavioural effects of an antihistamine is apparent in the evening after an evening dose, but will be smaller in the morning after a morning dose condition due to the excessive release of histamine shortly after awaking.
Goal is to develop an algorithm for determination of the timing and magnitude of the peak growth velocity in the individual patient with adolescent idiopathic scoliosis.
The pathophysiology of premature atherosclerosis is poorly understood. Patients often display few risk factors, but the clinical manifestations are evident. If atherosclerosis is expressed at a very young age, it is likely that besides the classical…
This study aims to test the efficiency and cost-effectiveness of a brief collaborative care intervention, in long-term users (>9months) of antidepressants in the general practice. This intervention will contain a patient-tailored treatment…
Acute challenges with cocaine and cannabis will induce two opposing dopaminergic states in the brain. Cocaine will stimulate dopamine release leading to hyperdopaminergia whereas cannabis will reduce central dopamine levels resulting in…
Recent data showed for the first time that IgE-ACPA antibodies have a direct biological immune response in mast cells of IgE-ACPA+ RA patients. Subsequently, mast cell targeting agents, such as anti-IgE therapy have rationale for application in RA…
To investigate the newly developed method to study lung density changes using CT-scan, in a small patient population. The relationship between radiation induced lung density changes and dose distribution/tumor location will be investigated.
Compared to standard care, Peer Driven Fellow Care combined with standard care will result in significantly less drop out and improved flow in the social rehabilitation process for homeless people, as well as in significant improvements in…
We hypothesize that a multidisciplinary group-based, self-management intervention is more effective on functioning in daily living and more cost-efficient than the active control group in patients with generalized osteoarthritis (GOA).
We hypothesize that the intervention will prove to be more effective than the control condition in achieving significant body weight loss at 3 months; We expect to observe significant changes in metabolic, psychological and behavioural parameters at…
Dronabinol impairs driving performance in light cannabis users, but not in heavy users, because of tolerance to the impairing effects.
Chronic heart failure (CHF) and chronic obstructive pulmonary disease (COPD) are important causes of morbidity and mortality. The prevalence and incidence of COPD as well as CHF are still rising. CHF is an important co-morbidity in COPD and vice…