969 resultaten
We hypothesize that systemic aPC will benefit patients with ALI/ARDS, as caused by inflammatory as well as infectious disorders, in terms of gas exchange, edema and capillary leak in these lungs, as well as in ventilator-days (duration of mechanical…
T-cell inhibition with Mycophenolate Mofetil (MMF) attenuates T-cell number, T-cell activation and T-cell – monocyte interaction, thereby minimizing the T-cell-driven inflammatory amplification loop. The latter will contribute to improvement of anti…
Local corticosteroid injections combined with usual care will have a positive effect on experienced recovery and will reduce pain at 3 and 12 months follow up compared to usual care alone.
There is a clinically and statistically significant difference in the percentage of patients who achieve and maintain clinical remission (defined as DAS < 1.6) and in functional ability and progression of radiological joint damage after 1…
Psychological factors (e.g. personality style) influence the course of CRPS-I but not the onset of this syndrome.
Does nurse-led follow up at home lead to improved quality of life an satifaction and a reduction of costs compared to medical follow up at the outpatient clinic, without compromising the medical condition of patients?
Ulcerative colitis is characterized by abnormal activation of the colon epithelium, which is considered to be a central pathogenic mechanism. Activation of colon epithelium cells in UC is associated with an abnormal high expression of Toll-like…
We hypothesize that e-health, consisting of internet guided monitoring and self management training online, for patients with atopic dermatitis combines cost savings with an improvement in quality of life.
Through stress the mast cells become activated and by their vaso-active substances the mucosa permeability will become increased. Therefore the mucosa is easier to penetrated by microbes and acid. This increased permeability will leads to…
Cognitive behaviour therapy and Self-examination therapy are both more effective in reducing depressive complaints than a waiting list control group.
A peptide representing the first eleven residues of hLF (hLF1-11) was shown to be effective in killing a variety of bacteria in vivo. The objective is to develop hLF1-11 as an effective and safe antibacterial and antifungal for the treatment of…
Bipolar devices will minimize the disadvantages of the monopolar device; risk of electrolyte disturbances by using saline irrigation, bleeding and the risk of nervous stimulation
Higher order aberrations, like spherical aberration, decreases visual performance.
The go4it programme will improve bmi, glucose tolerance and life style.
Early and aggressive treatment of rheumatoid arthritis according to a strict treatment protocol results in a 70% remission of the disease within 2 years.
Adjuvant intra-articular corticosteroids reduce the clinical signs and symptoms of bacterial arthritis and improve outcome.
Our hypothesis is that rebound thrombin generation occurs in ICU-patients after abrupt cessation of heparin treatment in terms of elevation of coagulation-markers and reduction fibrinolysis-markers; IV-weaning of heparin reduces this rebound…
The hypothesis to be tested is that the outcome in arm B is better than in arm A.
Correction of sub-clinical prolongation of coagulation tests (i.e., PTT between 14.7 – 20 seconds and platelets < 100 x 109/L) and transfusion of platelets in patients with Ascal®, significantly decreases the incidence of clinical significant…
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