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Identificatie van determinanten voor het lange termijn beloop van de obsessieve compulsieve stoornis.

De AMSTAD-OCD studie wil bijdragen aan de verbeteringen van de behandeling van OCS en aan het identificeren van determinanten van een chronisch beloop.

Een gerandomizeerde, dubbelblinde en placebo-gecontroleerde exploratieve studie ter evaluatie van een één week durende orale behandeling met R129160 (60 mg/dag) bij patiënten met chronische idiopathische urticaria.

Onderzoek naar de werkzaamheid, veiligheid en tolerantie van oraal R129160, 60 mg/dag in volwassen patiënten met chronische idiopathische urticaria (CIU).

Attention Control Training (ACT) in PTSD patients: a randomized controlled trial.

Does a Attention Control Training in patients in the experimental group with a PTSD prior to the TAU lead to a better outcome than in patients in the control group with a PTSD who have received a sham (fake) training prior to the TAU ? This is also…

Development, optimalisation and validation of the exercise diagnostics for functional iliac flow limitations in endurance athletes: blood pressure measurement, pedal force measurement an near infrared spectroscopy.

The use of a new protocol of exercise testing with use of blood pressure measurement, near infrared spectroscopy and pedal force measurement will improve the diagnostic value of the current decision algorithm used to diagnose functional iliac flow…

A retrospective study on compassionate use of Inotuzumab
Ozogamicin in infants and younger children with relapsed or
refractory acute lymphoblastic leukemia (ALL)

To retrospectively study Inotuzumab ozogamicin (InO) safety and toxicities in infants and younger children with relapsed or refractory ALL To study rates of response (morphologic response and minimal residual disease status) after therapy with InO

Healthy Picks: The effect of a multicomponent intervention on adolescents' veggie-rich foods and sugar-sweetened beverage consumption.

1. Sales data of VRPs in the canteens will increase during phases in which the designated products are nudged. 2. Sales data of SSBs in the vending machines will decrease during phases in which the designated products are nudged.

An evaluation of the Medtronic Gatekeeper system in the treatment of subjects with Gastroesophageal reflux disease (GERD).

N/A

Intra-operative cone-beam CT for detecting residual stones

Using Cone-Beam CT in percutaneous nephrolithotomy for detecting residual stones increases one-step stone-free rates and lowers the occurrence of stone-related events.

Ventilaton, inflammation, perfusion and structure in Neontale Lung patients

To develop a safe and fast MRI protocol for neonatal airway, lung and cardiac imaging in neonatal lung patients

European Randomized Study of Screening for Prostate Cancer.

Screening causes a difference in prostate cancer mortality of 20% or more.

Fibromyalgia on the move...! Randomised study on the feasibility and effect of fast-tracked diagnosis.

The aim of this study is to pass of the care for patients with fibromyalgia more efficiently through the cooperation of the rheumatologist and the nurse specialist. Because of this, the rheumatology outpatient department can be relieved partly,…

RAR-CLA and cognition

Daily supplementation of 3.5g RAR-CLA will slow down cognitive decline as compared to placebo

The Lucy Trial: Legitimizing Using Childhood memory rescripting early in the first Year

The primary aim of the study is to examine the effects of trauma treatment early on in schema therapy for patients with BPD on the decrease of BPD manifestations. Hypothesis: 1. The scores of the BPDSI of patients in condition A (starting with ImRs…

Growing up after surgery for Congenital Diaphragmatic Hernia (CDH): Problems for life? A study to evaluate optimal medical and psychosocial care in CDH Follow-Up till adulthood (CDH-FU)

to improve the medical care on long term follow up

Prospective Multicenter Microbiota Study for Evaluation and Monitoring of Severe Acute Pancreatitis

Gut dysbiosis drives disease processes driving morbidity and mortality in acute pancreatitis, such as infected pancreatic necrosis, and (persistent) multiple organ failure. A decrease in commensal members of the bacterial microbiome allows for…

exerCise inteRventIon STudy In NAFLD pAtients

We hypothesize that high interval physical exercise changes the contribution of adipose tissue and peripheral muscle to human NAFLD and aberrant glucose metabolism via gutmicrobiota mediated plasma metabolites.

A longitudinal non-invasive study of changes in urinary bladder contractility secondary to benign prostatic hyperplasia.

N/A

Ventilation with Lower Tidal Volumes as Compared to Traditional Tidal Volumes of Patients not Suffering from Acute Lung Injury.

We hypothesize that lung protective mechanical ventilation, using lower tidal volumes, attenuates mechanical ventilation induced pulmonary inflammation.

Improving metabolic control during and after pancreatic surgery using continuous glucose monitoring (TIMECOG trial): a pilot randomised controlled trial

We hypothesise that using a continuous subcutaneous glucose monitor during pancreatic surgery, will significantly improve percentage of time spent in glycaemic target range (i.e. glucose ≥ 4 mmol/l and < 10 mmol/l).

A randomised study about the effect on survival of hormonal therapy versus hormonal therapy plus local external radiation therapy in patients with primary diagnosed metastasised (M+) prostate cancer.

Today the standard therapy for patients primary diagnosed with M+ prostate cancer (bone metastasis) is systemic hormonal therapy. If standard hormonal treatment will be combined with local external radiation therapy of the prostate the survival may…