3040 resultaten
Lactate decreases TG-VLDL synthesis by the liver by decreased production. Since patients with FCH have a higher production, we hypothesize that they will have a significant decrease in their production.
The mission of the chronic ITP registry is to improve the knowledge of the treatment and course of patients with persistent of chronic ITP. The objective of the registry is to get more insight in the number of patients that need a treatment for…
1. Is a multidisciplinary cognitive behavioural lifestyle program more effective in losing weight and permanent weight loss for women with PCOS and obesity then regular care? 2. Is a multidisciplinary cognitive behavioural lifestyle program in…
In old age, reduction in physical function leads to loss of independence, the need for hospital and long-term nursing-home care, and premature death. Community-based complex interventions can be effective in maintaining physical function and…
A randomized controlled trial of geriatric liaison intervention in frail surgical oncology patients.
The primary objective of this study is to show that early detection of geriatric patients at risk of preventable functional decline following a surgical procedure under general anesthesia for a solid tumor, combined with a geriatric liaison…
Baseline variables such as Harm Avoidance and other personality, biological and electrophysiological measures will predict treatment outocme to an SSRI.
Adding a Combined Psychological Intervention to a very low calorie diet is more effective then a very low calorie diet followed by usual care in maintaining weight loss and improving glycaemic control, cardiovascular risk score, psychological…
We hypothesize that genetically programmed developmental differences in adipocytes are under direct regulation of fecal flora composition which thus plays an important role in obesity, body fat distribution ans systhemic inflammation.
The individual patient can make a well-informed choice for a treatment by using audio-visual aids.
BB3 will improve kidney function in the immediate post-transplant period in patients who have received a DCD kidney transplantation.
Several new imaging techniques have been developed in order to improve differentiation of colonic lesions, one of these is confocal endomicroscopy. The objective of the proposed study is to evaluate the feasibility and additional value of confocal…
To assess the tolerability and efficacy of the addition of oral tosedostat to standard induction therapy.
Cholesterol lowering by low fat diet and lovastatin will also reduce very long chain fatty acids in patients with X-ALD.
Feedback to the COPD patient about his condition and physical activity plays an important role in promoting self management. Within the current care for patients with COPD, there is a lack of insight into daily activities and lack of understanding…
We hypothesize that atopiform dermatitis is a separate entity with specific characteristics, which needs recognition in order to be diagnosed and treated appropriately.
To gain more insight into the pathogenetic processes involved in Sjogrens Syndrome(SS) bij analyzing the infiltrate and structural changes in salivary glands of SS patients and compare these findings to those in other (aspecific) inflammatory and…
Low dose nadroparin will prevent symptomatic and asymptomatic catheter-related deep vein thrombosis in patienten treated with high dose chemotherapy.
Continuous positive airway pressure on the deflated lung prevents total alveolar collapse, resulting in less local and systemic cytokine response, causing less pulmonary complications.
Patients with a wrist trauma represent a substantial part of the patient population at the Emergency Department. Most hospitals routinely carry out a radiological examination of patients following wrist trauma to exclude a distal radius fracture.…
By developing a model which predicts the risk of bleeding with coumarin use, patients can be treated more effectively, potentially avoiding the need for specific antidotes. Besides decreasing the risk of bleeding (potentially resulting in less…