1537 resultaten
To evaluate the response to adalimumab treatment in TNF-alpha blockade naïve patients and patients who failed prior other anti-TNF-alpha treatment and to understand the mechanisms underlying the clinical response to TNF-alpha blockade.
Awake craniotomy improves safety and efficacy during surgery for glioblastoma in eloquent areas
1: Long term use of fluoxetine causes the excitability of the primary motor area of the brain to change 2: Long term administration of fluoxetine causes the muscle activation patterns to change
We hypothesize that DVT can be safely ruled out by the LEFt rule in combination with the D-dimer test in 5-10% of pregnant women, and that a normal MRDTI safely rules out isolated pelvic vein thrombosis. We hypothesize that 7-10% of performed MRDTI’…
Individual-directed resilience training can reduce chronic stress and prevent burnout among students
Point of care testing with Fcal POCT will reduce substantial the referral rate of children with chronic GI symptoms to the paediatrician.
A newly developed artificial saliva spray (Novospray) alleviates the feeling of a dry mouth in patients suffering from xerostomia better than placebo.
Heart rate variability measures correlate with pain intensity in patients with advanced cancer.
DBS in the nucleus accumbens can lead to long-term improvement of obsessive-compulsive symptoms and funtioning, without unacceptable side-effects.
The hypothesis to be proved in this study project is: “first attempt success ratio of peripheral intravenous catheter placement will increase up to 90% in adult patients when a Venflon™ Pro Safety with BD InstaFlash™ Needle Technology is inserted,…
Fecal Immunochemical Testing as a Tool to Determine the Need for Colonoscopy in Symptomatic Patients
Using two FIT tests in symptomatic patients prior to colonoscopy can be a useful preselection tool to determine the need for colonoscopy in symptomatic patients.
Botulinum toxin type A injection of the prostate causes relaxation and cellular apoptosis and by this way will relieve lower urinary tract symptoms in patients with benign prostatic hyperplasia.
We hypothesize that subjects with NASH produce more ethanol after a mixed meal tolerance test than subjects with a healthy liver after receiving a infusion with fomepizole.
Biomarkers for predicting disease severity in emergency department patients with suspected infection
Novel biomarkers can aid in the early identification of sepsis, and can be useful for risk stratification at the ED in patients with a suspected infection.
We expect changes in each of the three tasks, with less words remembered (15 word test), a larger Simon effect (Simon task) and slower performance (TMT) in the repeated assessment compared to the first assessment. We also expect changes in each of…
We hypothesize that in many patients there will be an inconsistency between administrating medication and registration in the EHR of more than 15 minutes. Making retrospective studies drawing conclusions on data from the EHR less reliable.
Reducing the dose in the setting of therapeutic drug monitoring (TDM) does not affect clinical disease activity and safety, while it will reduce costs.
The different processing of formulas will have an effect on stool characteristics such as consistency, frequency, amount and colour.
The aim of the study is: 1. To investigate the benefits and risks of hormonal substitution after prophylactic adnectomy in women with an increased risk for breast- and/or ovarian cancer due to a genetic predisposition; 2. To compare the effects and…
The combination of PARP and PD-L1 inhibition has a synergistic effect and will result in progression free survival improvement.