391 resultaten
In patients with Crohn’s disease, absorption of bile salts in the ileum into the enterohepatic circulation is thought to be impaired, either through active ileal inflammation or through faster passage of intestinal contents through small and large…
The purpose of this prospective, observational one- centre study is to evaluate the relation between atrial fibrillation and clinical characteristics, including isolated aphasia, in a population of patients with ischemic stroke due to either atrial…
While prophylactic use of acetylsalicylic acid and Non Steroidal Anti-Inflammatory Drugs (NSAID’s) is often used concomitantly for long periods of time, there is concern about the safety of this combination in preventing cardiovascular disease.…
It is expected that workers in the intervention group (ECO) return to work faster than workers in the usual care group (CAU). Furthermore, it is expected that workers in the intervention group have a larger reduction in depressive, anxiety or…
The QST battery of the DFNS (Rolke 2006) is a comprehensive measurement for neurosensory function. The current study is a phase 0 study to assess the repeatability of the QST battery of the DFNS and the intra-dermal capsaicin model.
This non-inferiority study specifies as a null hypothesis that ICG enhanced NIRF imaging is inferior in detecting sentinel lymph nodes compared to the current standard treatment (technetium-99m combined with Patent Blue).
Does computer tailored feedback improve the lifestyle of COPD patient?
Objectives: 1. To investigate the added effects of eplerenone on top of ACEi, with and without dietary sodium restriction, on residual albuminuria, hypertension, and tubular injury markers, in patients with diabetic nephropathy; 2. To investigate…
Our primary objective is to determine whether testing for molecular markers, i.e. hrHPV, CADM1/MAL methylation and combinations thereof, yields a higher sensitivity and specificity for the detection of CIN2/3 or cancer after treatment in comparison…
Of major concern in dementia are accompanying behavioral problems. Clinically relevant behavioral problems (aggression, agitation, apathy) occur frequently and are mostly chronical. They result in considerable distress and workload for nursing staff…
Improvement of favourable outcome by consecuetive treatment of tranexamic acid before aneurysm treatment with switch to acetylsalicylic acid short before start of treatment and continued for two weeks.
We aim to determine the effectiveness and cost-effectiveness of multilevel botulinum-toxin type A injections in combination with a 12-week period of intensive functional physiotherapy exercises (BtA+iPT) and compare this with the effectiveness and…
In the treatment of a uterine prolapse stage 2 or higher sacrospinous fixation will result in equal or lower recurrence rate of prolapse than a vaginal hysterectomy.
Compared to standard care, Peer Driven Fellow Care combined with standard care will result in significantly less drop out and improved flow in the social rehabilitation process for homeless people, as well as in significant improvements in…
We hypothesize that a multidisciplinary group-based, self-management intervention is more effective on functioning in daily living and more cost-efficient than the active control group in patients with generalized osteoarthritis (GOA).
We hypothesize that the intervention will prove to be more effective than the control condition in achieving significant body weight loss at 3 months; We expect to observe significant changes in metabolic, psychological and behavioural parameters at…
The molecular expression profile of upper and lower airways differs between allergic asthmatics and healthy controls.
Dronabinol impairs driving performance in light cannabis users, but not in heavy users, because of tolerance to the impairing effects.
Cancer is a serious and potentially fatal disease. Scientific studies indicate that good social support is of great imporance for physical and emotional well being. At the same time there is little knowlegde about what specific social reactions are…
1. Dutch patients with Addison's disease treated with suboptimal glucocorticoid replacement therapy have a reduced QoL; 2. Prevalence of the metabolic syndrome is higher among patients with Addison's disease treated with suboptimal…