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Observational cohort of patients treated with stereotactic radiotherapy for Oligo LYMPh nOde and other soft tissue metastasiS; the OLYMPOS cohort

The main clinical challenge remains to identify patients who may benefit from aggressive local treatment (stereotactic radiotherapy, SBRT) of soft tissue oligometastases: for which patients can systemic treatment be postponed? Patients who are…

Effect of an exercise program on the jump-landing technique in athletes.

Has a coach supervised intervention program targeting jump-landing technique effect on the incidence of lower extremity injuries.

The effects of propranolol on fear of wisdom tooth removal: A randomized, placebo-controlled, double-blind, parallel design trial

We hypothesize that subjects taking propranolol (1h preoperative and directly postoperative) will report: 1. lower levels of state anxiety 2. lower levels of dental trait anxiety 3. lower levels of aversive traumatic memory 4. lower levels of…

De invloed van rookstatus op de behandeling van longkanker met immunotherapie

Mortality will be lower in patients who do not smoke during treatment of non-small cell lung carcinoma with PD-L1-inhibitors compared to patients who smoke during their treatment with PD-L1-inhibitors.

Contact-based Intervention for Infants during Transition to Centre-based Care

1. Compared to the control group, 4 weeks and 8 weeks after the start of centre-based care infants in the intervention group will show: - Lower morning and afternoon levels of salivary cortisol - Less disruption of the gut microbiota and an improved…

A relapse prevention study for anxiety patients who want to discontinue antidepressant medication.

The hypothesis is that offering CBT in a group format while discontinuing antidepressant medication will reduce the high relapse rates in remitted anxiety disorder patients who discontinue pharmacological treatment.

Stapler or endoloop closure of the appendiceal stump in laparoscopic appendectomy.

Superficial and intra-abdominal infections: 8% in the standard loop group to 4% in the endoloop closure group.

eNose in Head and Neck Cancer.

we hypothesize that an electronic nose can discriminate the VOC pattern in exhaled breath between patients with Head and Neck Cancer from healthy controls.

eNose in Colorectal Cancer.

we hypothesize that an electronic nose can discriminate the VOC pattern in exhaled breath between patients with colorectal cancer and healthy controls.

Convalescent antilichaam gemedieerde behandeling van COVID-19 infecties bij patiënten met B-cel disfunctie, een gerandomiseerde studie (COVID-Compromise Studie).

Er zijn meldingen gemaakt van een ernstiger verloop van COVID-19-infecties bij patiënten met een verminderd immuunsysteem, zoals patiënten met aangeboren immuunafwijkingen, (hematologische) maligniteiten of patiënten die medicatie gebruiken die het…

Klinische evaluatie van het CARMAT-kunsthart voor patiënten met eindstadium hartfalen

Het doel van deze klinische studie is het aantonen van de veiligheid en prestatie van het CARMAT-kunsthart in patiënten metvergevorderd hartfalen.