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In this study we explore the feasibility of the sequential use of FLAMSA chemotherapy and T cell depleted reduced intensity conditioning allogeneic stem cell transplantation followed by donor lymphocyte infusion at 3 and 6 months after…
The objective of this study is to assess the technical feasibility of the EsoFLIP dilation balloon in the treatment of achalasia.
Whole blood thrombin generation measurement is comparable to plasma thrombin generation in clinical setting.
The goal of this trial is to investigate the efficacy of the IMP during c-section with and without the use of Sufenta: As well as start of action, duration of action, the degree of motor and sensory block as well as the hight of the block itselfs…
The primary hypothesis is that normo-ovulatory women with a BRCA mutation have lower levels of AMH compared to normo-ovulatory BRCA mutation-negative women, with at least a difference of 0.40 ng/ml, suggesting an effect size of three years in…
Laparoscopic Fluorescent near-infrared imaging using ICG can accurately detect liver metastases from uveal melanoma intra operatively.
We expect an improvement in psychological flexibility and a decrease in pain interference in daily life or in fatigue. Furthermore, we expect a decrease in depression and anxiety symptoms.
An intervention with Methylphenidate, Melatonin or Light Therapy will lead to changes in visual functioning.
Think different: effectiveness of an online training for children with obsessive-compulsive disorder
The aim of the present study is to improve treatment for children with OCD by adding an online Cognitive Bias Modification-Interpretation (CBM-I) training as a pre-treatment to cognitive behavioural therapy (CBT). CBM-I is compared with a waitlist…
People with aphasia have problems with communicating. Because communication is very important in the society, these group suffers from a smaller social network, diminished social participation and as a result of this, loneliness, a loss of autonomy…
Tailored exercise is more effective in regaining functional ability, in comparison to usual care, in adolescents diagnosed with HMS/EDS-HT
Intravesical instillation of BCG is a widely accepted strategy to prevent recurrence of non muscle invasive bladder cancer. The most accepted treatment schedule is induction of BCG: weeks 1 through 6 plus maintenance (weeks 1,2,3) at months 3,6 and…
We hypothesize that selfmanagement support via an internet based service in addition to usual care will improve health related quality of life in patients with severe asthma who have participated pulmonary rehabilitation in specialized asthma…
We hypothesise that there would be no significant difference between the preoperative planning between different orthopedic surgeons.
The objective of the proposed study is the intraoperative detection of tumor tissue of peritoneal carcinomatosis of colorectal origin by using a near-infrared fluorophore, 800CW, conjugated to bevacizumab resulting in a bevacizumab-IRDye800CW…
HIV-infection and antiretroviral therapy use may lead to a diminished neurological and neurocognitive performance in HIV-infected children.
Continuous Passive Motion in the early post-operative periode after knee surgery is beneficiary for the rehabilation process in children with cerebral palsy.
The aim of this study is to correlate the score on a functional performance test battery to the occurence of ACL reruptures and contralateral ruptures. We hypothesize that athletes with a limb symmetry index of <100% on strength or hoptests…
To determine the outcome of hand function of (ex)patients with flexor tendon rupture 7 – 10 years after surgical repair. We expect that subjects with flexor tendon injury have significantly worse hand function than healthy subjects.