450 resultaten
Respiratory Syncytial Virus (RSV) is still the leading cause of hospitalization of children under 5 years of age. Currently, there is no effective treatment licensed for an ongoing RSV infection. Therefore, Intravacc develops a live-attenuated…
The main objective of this study is to compare upper extremity dysfunction (UED) following slender TRPCI using small bore catheters (5F) compared to standard PCI using regular size guiding catheters (6F) and conventional stent techniques at two…
Tacrolimus (FK506) is the main immunosuppressant that is prescribed after kidney transplantation. One of the disadvantages of Tacrolimus is the small therapeutic window. In transplantation patients therapeutic drug monitoring is routinely performed…
the present study investigates whether a small-scale stay in an enriched green environment in a care center is related to a slower progression of cognitive functions, better mood, less behavioral problems, and a higher quality than if standard care…
The adherence of NOACs in atrial fibrillation in specific subgroups is low. Identifying these non-adherent patients in daily clinical practice is important to minimise stroke and bleeding risk. We hypothesize that NOACs are relatively often…
HYPOTHESES: We hypothesize that the PAMA condition in comparison to the Usual Care condition will: 2. Lead to more high risk smokers engaging to quit 3. Lead to more informed decision to quit smoking by smoking patients 4. Lead to more evidence…
1. An early screening at 1y of corrected age will identify preterm children with an increased risk of developing visual processing dysfunctions 2. Early visual rehabilitation from 1y of corrected age will benefit the visual and neurocognitive…
By means of image-guided surgery, we can navigate the procedure by visualization of pre-operative planned MR and/or CT based 3D models and providing the surgeon with real-time feedback on the position of the surgical tool within this model and more…
LRRK2 activity is linked to central mechanisms of Parkinson’s disease pathology through its role in lysosomal function, and LRRK2 kinase inhibitors, such as DNL201 (IND Number: 133665) represent a new class of therapeutics with potential to address…
Obesity is significantly associated with Atrial Fibrillation (AF), and, interestingly, if obese patients loose weight, AF dissapears in 50% of the cohort. On the other hand, adipose tissue (AT) functioning alters up weightchange. Therefore we…
Ex vivo organoid response correlates to in vivo response to standard first line treatment in mCRC patients on a metastasis level, therefore organoids can be used to predict response to therapy and select patients for a specific treatment.
MBSR influences (1) emotional processing and (2) body awareness. The effect of MBSR on emotional processing is (3) mediated by body awareness.
Primary objective 1) To assess and compare overall QOL during each subsequent line and type of therapy. Secondary objectives: 2) To assess and compare therapy satisfaction / decision regret during each subsequent line and type of therapy. 3) To…
Inhaled levodopa provides more rapid symptom relief than orally administered levodopa
Onlay and sublay mesh reinforcement after midline laparotomies in patients with an increased risk for the development of incisional hernias (IHs) resulted in less IHs compared to patients that received the conventional closure technique at two years…
Recurrent respiratory tract infections (RTIs) affect 15-20% of children aged 0-5 years and cause high disease burden, frequent doctor visits and are one of the main reasons for hospital admission in childhood. Despite the common use of co-…
Objective: The overall aim of this project is to correlate the characteristic changes of the deformation-area loop to the properties of the pressure-volume curve. We hypothesize that the systolic slope of the deformation-area loop relates to the end…
Music interventions will reduce anxiety and pain in patients undergoing a nuss bar procedure due to pectus excavatum
We expect to make recommendations in choosing between the PSFS or PSFS-D answering option and to describe important items from a patient's perspective regarding relevance, comprehensiveness and comprehensibility. We expect high correlation…