577 resultaten
- The intervention prevents decline in Quality of Life (primary outcome), perceived stress and communication in the relationship in PwD, as compared to before the intervention? - The caregiver has improved self-efficacy (primary outcome) and…
This study will allow us to define the optimal dosis and value of these HPV DNA vaccines for the treatment of HPV16+ (pre)malignancies.
Clinical decision support systems (CDSSs) provide alerts warning the physician for DDIs during prescribing of medication. Lack of fit between a clinical setting and CDSS alerts cause low specificity (i.e. low clinical relevance) of alerts. Low…
To assess the accuracy and the clinical feasibility of a Bayesian-based, patient-individualized, pharmacodynamic advisory system to optimize propofol effect-compartment-controlled administration using the qCON index as a controlled variable versus…
The aim of this study is to critically examine the effect of EMDR added to ERP on treatment acceptability and outcome in patients with OCD.
The primary aim of this project is to further elucidate the (neural) mechanisms of ketamine, which may underlie its (rapid) antidepressant response.
Malignant peritoneal mesothelioma (MPM) is an uncommon but aggressive neoplasm. MPM has low survival rates of approximately one year even after palliative surgery and/or systemic chemotherapy. Recent advances in treatment strategies focusing on…
In this study we aim to investigate whether intestinal acetate production by gutmicrobiota is related to (postprandial) plasma acetate levels, insulin secretion/sensitivity and the CNS regulation of food intake (fMRI).
The purpose of this study is data collection of continuous noninvasive and invasive arterial pressure waveform signals in intensive care patients with the Clearsight and Flotrac monitor. The collected digital pressure waveform data will be used to…
Main hypothesis: Master Your Symptoms is effective in improving the perceived physical health-related related quality of life of patients with mild to moderate medically unexplained symptoms. Secondary hypotheses: - Master your Symptoms is cost-…
The TSAT/hepcidin ratio can be used as a diagnostic tool to differentiate between IRIDA and other disorders presenting with iron deficiency anemia with a high specificity. TSAT = transferrin saturation IRIDA = Iron Refractory Iron Deficiency Anemia
Can imaging surveillance frequency be safely reduced in a select group of EVAR patients, i.e. patients with an asymptomatic infrarenal abdominal aortic aneurysm (AAA) that underwent EVAR without abnormalities on the initial postoperative CTA.
The aim of the study is to evaluate the effectiveness of school-based skills-training programs targeting skills to deal with performance anxiety or social skills in promoting the mental health of adolescents and to examine moderators of its…
We hypothesise that zoned high compression shorts significantly decrease groin pain in football players without reducing performance.
The objective of the study is to determine whether optical measurements can support pulse detection during cardiopulmonary resuscitation. The optical measurements will be compared with standard measurements such as palpation,…
The microbiota composition can predict if patients with metastatic and/or irresectable CRC will respond to systemic treatment and/or experience zero to limited chemotoxicity. Secondly, we postulate that patients who retain the same favorable…
We expect high correlation coefficients (r ≥ 0.60) between the Cervical Range Of Motion (CROM) device and the Senscoordination 3D Cervical Trainer (SCT), resulting in good concurrent validity. Acceptable reliability was expected (an IntraClass…
There is a possibility that the Philadelphia neck collar gives better results than the stifneck collar on the proposed outcomes.