6174 resultaten
We hypothesize that the use of a GnRH-antagonist in cycles with Mild Ovarian Hyperstimulation (MOH) combined with Intrauterine insemination (IUI) programs significantly improves live birth rates compared with MOH and a placebo.
The hypothesis to be tested is that arm B is tolerable and that the outcome in arm B is better than in arm A.
Calculate the incidence of eclampsia; cardiac arrest and perimortem caesarean sectio in pregnancy or puerperium in the Netherlands.
1. The deafferentiation during spinal anesthesia changes the connectivity in resting-state networks in healthy volunteers; 2. The deafferentiation during spinal anesthesia changes pain perception and has sedetive effects.
Children with CP experience limitations in motor activities and participation in the community, predominantly caused by impairments in muscle function. Aside from abnormal posturing due to spasticity, muscle weakness can significantly contribute to…
RR with prompting results in a higher rate of self-initiated toileting and a decrease in urinary/faecal accidents. For children who do not attain continence with RR and prompting alone, an add-on restoring procedure will result in a higher rate of…
Client-centred occupational therapy according to the Occupational Performance Process Model will be more effective in improving daily functioning and societal participation of patients with multiple sclerosis than usual-care occupational therapy.
We expect that with a target of 1.5-2.0x baseline aPTT or with LMWH the primary composite endpoint will be reached in 60% of patients compared to 70% in usual care. To show non-inferiority with a significance level (alpha) of 5%, power of 80% and a…
Long-term use of 6-thioguanine is more hepatotoxic, based on histopathological findings, as compared with the long-term use of azathioprine and 6-mercaptopurine in inflammatory bowel disease patients.
We expect an incidence of delirium in our control group of 30%. This is based on literature documenting incidence of delirium in neurosurgical patients in a northern European population of 29-33%. The expected effect cannot be based on previous…
CE and AFI are equally effective for the detection of neoplastic lesions in patients undergoing colonoscopic surveillance for UC. Also, the combined use of AFI plus NBI and the use of CE have an equal sensitivity and specificity for the…
Refinement of the CHIP prediction rule will lead to a more efficient use of head CT in patients with minor head injury
Observational study
3D printed tailormade assistive aids may better fulfill the requirements and needs of clients with disabilities to support them in performing their activities of daily living than the currently available aids or handmade aids provided by…
We hypothesise that the new MRI protocol will be superior to the previous protocol at calculating lung volumes and central airways dimensions, and subsequently improve the detection and quantification of TA in both CF and asthma disease pathologies.
We hypothesize that providing personalized feedback on one’s health and diet will help low socio-economic status consumers to improve their dietary pattern, and even more so if personalized dietary advice is added to the feedback. The pilot study…
Organoids can be cultured from pancreatic ductal biopsies, obtained from chronic pancreatitis patients, to study electrolyte and fluid secretion.
The sentinel node procedure is feasible and safe in women with a first recurrent vulva cancer
The aim of this study is threefold: (1) to test the effectiveness of OVK in reducing symptoms of depression compared to treatment as usual (TAU), (2) to identify mechanisms that can explain program effects, and (3) to test the effects of OVK on…