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Intra-operatieve fluorescente beeldvorming van schildwachtklieren bij baarmoederhalskankerpatienten.

Fluorescent near-infrared imaging can accurately detect sentinel lymph nodes non-invasively during lymphadenectomy in cervical cancer patients.

Treatment of anxiety disorders in children with Autism Spectrum Disorders (ASD).

The aims of the study are: 1. To compare the effectiveness of Cognitive Behavioral Therapy (CBT) for anxiety disorders between children with ASD and children without ASD; 2. To compare the (cost-) effectiveness of CBT to Treatment As Usual (TAU) for…

High-dose baclofen for the treatment of alcohol addiction.

N/A

The effect of nutritional supplementation with a disease specific tube feed on the postprandial plasma glucose reponse in type 2 diabetic patients at baseline and after 6 and 12 weeks of supplementation.

Usage of disease specific tube feed will improve glucose control in diabetic patients.

Waterhoudend contrast vs. oliehoudend contrast voor het doorspuiten van de eileiders tijdens een baarmoederfoto – Effecten op de schildklierfunctie van het kind

See summary.

Validation of pelvic floor related symptom and Quality of Life questionnaires in Dutch patients.

Pelvic floor related symptom and Quality of Life questionnaires (IIQ-7, UDI-6, IIEF-5, PISQ-12, PFIQ-7, PFDI-20, FISI, FIQL) in Dutch are valid instruments, which can be used reliably in daily practice and clinical research.

Selective laser trabeculoplasty (SLT) as replacement therapy in glaucoma patients

1. does pseudophakia influence intra ocular pressure (IOP) lowering effect of SLT? 2. the effect of SLT relies on an inflammatory reaction. Anti-inflammatory therapy is often used immediately following SLT, does this influence the IOP lowering…

Local anaesthesia and Bellovac ABT.

To quantify the amount of local anaesthetic in blood and tissue fluid in the Bellovac ABT system and in the blood circulation of the patient. The primary objective is to quantify the cumulative ropivacaine level when the blood should be retransfused…

Clinical study to evaluate safety, tolerability and effects on the immune system of a common cold vaccine in healthy adults

Respiratory Syncytial Virus (RSV) is still the leading cause of hospitalization of children under 5 years of age. Currently, there is no effective treatment licensed for an ongoing RSV infection. Therefore, Intravacc develops a live-attenuated…

Hypothermic Oxygenated Perfusion of Liver Grafts Donated after Circulatory Death in
Liver Transplantation - A Phase 1 Clinical Trial

Two hours of end-ischemic hypothermic oxygenated perfusion via both the hepatic artery and the portal vein is feasible and safe in resuscitating liver grafts procured from donation after circulatory death donors.

Effects of a participatory work stress prevention approach in primary education in the Netherlands

At two-year follow up, employees of the intervention schools report significantly lower levels of work stress and work stress risks as compared to employees of the control schools

Study on the effects of a growing-up milk (GUM)on infections in healthy children

Consumption of the new developed GUM will decrease the incidence of upper respiratory tract infections (URTI) and/or decrease the duration of acute gastrointestinal tract infections (GITI) in Asian toddlers

A pilot, double-blind, randomised, placebo-controlled, exploratory study to investigate the safety and effect of Calf Intestinal Alkaline Phosphatase in patients with sepsis.

Unlike other potential sepsis treatments, Alkaline Phosphatase has been shown to act at the front end of the inflammatory cascade. By doing so, it eliminates the root cause of the SIRS, and prevents the progression into sepsis and septic shock.

Stop worrying.

A self help brochure will help people decrease their excessive worrying. and telephonic support will increase the effect.

Effects of low-fat vs high-fat diet on lipid accumulation in liver and skeletal muscle in overweight men.

A high fat-diet can influence IMCL and IHL in rodents and in humans, the time-course of peripheral lipid accumulation in liver and skeletal muscle while switching from a low-fat to a high-fat diet is unknown.

The TIKI study: Treatment with or without IVIG in Kids with acute ITP.

The primary objective is to investigate to what extent early IVIG treatment in children with newly diagnosed acute ITP reduces the risk of development of chronic disease. Secondary objectives are: 1. To estimate the alteration in the clinical…

Skeletal muscle protein synthesis in elderly after bolus intake of oral nutritional supplements.

A relatively high quantity of dietary protein is needed to stimulate muscle protein synthesis in elderly.

Heeft het zin om mensen zoals huisartsen, politieagenten, docenten, thuiszorgmedewerkers, etc te trainen om beter suïcidaal gedrag te herkennen, vaardiger te zijn in het contact maken met suïcidale mensen en hen te leren hoe ze suïcidale mensen kunnen motiveren voor en verwijzen naar professionele hulp?

1. Gatekeeper training is effective in enhancing relevant skills 2. Gatekeeper training will diminish rates of (attempted) suicides at regional level 3. The intervention is cost-effective relative to routine medical care

Monitoring of exhaled nitric oxide (FENO) to tailor the lowest effective dose of oral corticosteroids in severe asthma (MONOSA-Study).

1. Daily home monitoring of exhaled nitric oxide (FENO) in patients with severe asthma facilitate tapering of oral corticosteroids to the lowest possible dose, leading to a reduction of total corticosteroid consumption; 2. This can be achieved…

Improving lifestyle adherence in patients with high risk of cardiovascular diseases in General Practice.

1. What is the effect of active patient involvement by the practice nurse on decisions regarding cardiovascular risk reduction, adherence to lifestyle advice, cardiovascular risk and other outcomes at 12 weeks and 52 weeks, compared to usual care?…