17983 resultaten
The null hypothesis of this research is that the ZCQ outcome of PDI surgery is similar to the ZCQ outcome os surgical decompression at 1 year after surgery.
1. Comprehensive geriatric assessment has no benefits in selecting patients fit for chemotherapeutic treatment, compared to clinical judgement by the medical oncologist; 2. Observational report of the functional outcome of treating ovarian carcinoma…
We hypothesize that age-related changes in hepatic and intestinal drug metabolism affect the pharmacokinetics of paracetamol.
There is no difference between the diagnostic accuracy of SIRS criteria and qSOFA score in identifying sepsis in undifferentiated patients at the ED.
Recent pre-clinical experiments demonstrated that sorafenib in Oatp1b2(-/-) mice had 8-fold increased sorafenib-glucuronide blood concentrations.OATP1B1 and 1B3 are highly expressed in the human liver and facilitate the hepatocellular uptake of…
We hypothesize that CTC detection through diagnostic leukapheresis improves the detection rate among ER+, N+ primary breast cancer who have received 5 years of adjuvant endocrine therapy and will be a promising technique for risk classification in…
rhDNase targeted to the peripheral airways improves lung function in children with CF and a stable clinical condition.
The open preperitoneal approach in inguinal hernia repair might have the benefit of a mesh in the preferred space without the disadvantages of an endoscopic procedure.
Family Group Conferences will improve disability-management self-efficacy and participation in patients with amputation, acquired brain injury and spinal cord injury and their relatives
Outpatient LMHW treatment in patients with objectively proven non-massive pulmonary embolism is efficacious and safe.
In EPF, the sequential combination of mifepristone with misoprostol is superior to the use of misoprostol alone in terms of complete evacuation of products of conception, patient satisfaction, complications, side effects and costs.
To assess the impact of the physical form of five different cocoa matrices on the bioavailability of the monomeric flavan-3-ols.
Treatment with Botox will give a better healing rate for anal fissures compared to treatment with isosorbidedinitrate ointment.
We hypothesize that Network Pain Rehabilitation Limburg will be feasible in daily practice based on the found barriers and facillitators and perceived quality of care. Moreover, the effect of the different treatments on the physical functioning of…
Fluorescent near-infrared imaging can accurately detect lymph nodes percutaneously and non-invasively during SLNP in vulvar cancer patients.
Multiple Endocrine Neoplasia type 1 (MEN1) and Von Hippel-Lindau disease (VHL) are rare autosomal dominantly inherited disorders characterized by the occurrence of various tumors. Therefore, mutation carriers undergo regular screening (yearly for…
The primary objective of the study is to investigate whether an induced nocebo effect can be effectively reduced by open-label counterconditioning, combined with open-label verbal suggestions, as compared to continued nocebo conditioning and…
The Maastricht brace is a new develwoped thoracolumbar brace that improves wearability and quality of life, while maintaining efficiency and function
Compare the gametocytocidal and transmission reducing activity of artemether-lumefantrine (AL) with and without a single dose of 0.25mg/kg primaquine (PQ) and sulfadoxine-pyrimethamine with amodiaquine (SPAQ) with and without single dose of 1.66mg/…