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The effect of electrical neurostimulation on collateral perfusion during acute coronary occlusion.

Neurostimulation can improve collateral perfusion measured as a Pw/Pa ratio, during acute coronary occlusione.

High-dose baclofen for the treatment of alcohol addiction.

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The effect of nutritional supplementation with a disease specific tube feed on the postprandial plasma glucose reponse in type 2 diabetic patients at baseline and after 6 and 12 weeks of supplementation.

Usage of disease specific tube feed will improve glucose control in diabetic patients.

Waterhoudend contrast vs. oliehoudend contrast voor het doorspuiten van de eileiders tijdens een baarmoederfoto – Effecten op de schildklierfunctie van het kind

See summary.

Validation of pelvic floor related symptom and Quality of Life questionnaires in Dutch patients.

Pelvic floor related symptom and Quality of Life questionnaires (IIQ-7, UDI-6, IIEF-5, PISQ-12, PFIQ-7, PFDI-20, FISI, FIQL) in Dutch are valid instruments, which can be used reliably in daily practice and clinical research.

Selective laser trabeculoplasty (SLT) as replacement therapy in glaucoma patients

1. does pseudophakia influence intra ocular pressure (IOP) lowering effect of SLT? 2. the effect of SLT relies on an inflammatory reaction. Anti-inflammatory therapy is often used immediately following SLT, does this influence the IOP lowering…

Local anaesthesia and Bellovac ABT.

To quantify the amount of local anaesthetic in blood and tissue fluid in the Bellovac ABT system and in the blood circulation of the patient. The primary objective is to quantify the cumulative ropivacaine level when the blood should be retransfused…

Impact of clinical decision support on paediatric emergency care.

Evidence based medicine is the standard for current clinical practice. Guidelines and decision rules are developed to support medical decision making. Application of decision rules are supposed to improve efficiency and quality of care by early…

Amlexanox oral adhesive pellicles treats MiRAU.

Amlexanox is not available in China yet or has not been generally accepted in clinical treatment. To explore the effectiveness of amlexanox oral adhesive pellicles in the treatment of minor recurrent aphthous ulcers.

Assessment of a novel strategy to attenuate muscle mass loss during 2 weeks of bed rest

We hypothesize that applying BFR will decrease the loss in leg muscle mass during 2 weeks of bed rest.

The long-term effect of 10 days cold in diabetic patients.

The beneficial effect of cold acclimation on insulin sensitivity is reproducible and the effect wil sustain for a longer period of time. Besides insulin sensitivity, cold acclimation also has beneficial effects on cardiovascular risk factors in type…

Investigating the immune response to COVID-19 vaccination in lung transplantation patients (COVALENT study)

Lung transplantation patients are immunocompromised due to antirejection therapy. The effectivity of the COVID-19 vaccination in this high-risk patient group is completely unknown.

Intramuscular or combined intramuscular/intra-arterial administration of bone marrow mononuclear cells in patients with advanced limb ischemia.

The primary aim of our study was to test the feasibility and safety of exclusively intramuscular, and combined intramuscular/intra-arterial delivery of Bone marrow Mononuclear Cells (BMC) in patients with advanced without conventional options for…

Physical therapy to improve physical activity by exercise during hospitalization

Patients in the intervention group are more physically actice during and the 2nd week after hospitalisation.

The effect of ultraviolet radiation on the skin manifestations of patients with dermatomyositis.

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Antidepressants during pregnancy. Risk-benefit study for mother and child.

The use of modern antidepressants during pregnancy is associated with changes in fetal movement and development and can lead to seroius withdrawal syndromes after birth. Antidepressant use as well as discontinuation of medication during pregnancy…

Video Autofluorescence Imaging for Detection of Adenomatous Polyps of the colon in Intermediate and High-risk Patients.

The aims of the study are: 1. to assess the clinical utility and feasibility of AFI surveillance colonoscopy in patients with intermediate or high risk for adenomatous polyps; 2. to determine the additional value of AFI in the detection of polyps…

Pharmacological Treatment of Depression.

1. Imipramine and Venlafaxine are comparable in efficacy in inpatients with a major depression; 2. Imipramine and Venlafaxine are comparable in tolerability; 3. Patients with a Venlafaxine plasma level < 195 µg/L show comparable…

The SHAPE study.

We hypothesise that exercise may reduce risk of breast cancer, either directly or indirectly through a reduction in abdominal fat mass, by favouring the sex hormone profile and decreased insulin. Because the association between breast cancer and…

Comparison of the effectiveness of a behavioural graded activity program and manual therapy in patients with sub-acute neck pain.

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