123 resultaten
A 10% point prevalence abstinence in the control condition (usual care) is expected. The web-based multiple tailored smoking cessation programme alone is expected to yield an additional 10% of abstinent respondents, while the combination of multiple…
PCI will prevent brain metastases, even for patients with other sites of failure, and will improve the neurological disease-free survival, and hence quality of life. PCI will also be cost-effective.
We hypothesize that endoscopic resection (ER) of early neoplasia arising in Barrett esophagus (BE) using the multiband mucosectomy (MBM) technique is equally effective in removing early neoplasia, but may be faster, cheaper and possibly safer than…
The action of statins in CRC is dependant on the expression of elements of the BMP pathway.
The intervention group, receiving a lifestyle intervention, will significantly improve physical activity and dietary behavior, and thus prevent weight gain compared to the control group at the short (6 months) and the longer term (12 months).
Patients with a poor prognosis should get a cheaper plastic stent and patients with a longer prognosis shoud get a more expensive metal stent.
The FECAL trial, Fecal therapy to Eliminate Clostridium difficile Associated Longstanding diarrhoea.
Hypothesis: An important factor in recurrence of Clostridium difficile associated diarrhoea is persistent disturbance of intestinal flora. With restoration of flora by feces from a healthy donor future recurrences can be prevented.
The withdrawal, reduction or substitution of fall-risk increasing drugs will reduce fall risk in the elderly.
Supplementation of infant formula with a combination of pre- and probiotics may protect infants against infectious complications such as diarrhoea and respiratory infections. We speculate that the combination of pre and probiotics is better…
Patients with a combination of COPD and CHF who receive a small-group community based reactivation programme will have a higher exercise capacity and quality of life after completing the programme compared to before.
The primary potential effect of the intervention is a reduction of the severity of urinary incontinence in the participating women. Secondary expected effects are improvement of the quality of life of incontinent women and reduction of the costs of…
The nutritional supplementations of prebiotics and synbiotics are effective in prevention and treatment of the symptoms of infections in infants.
The primary objective of the study is to determine: • Adherence for second round CRC screening with one-sample iFOBT (OC-Hemodia Latex) comparing annual, biennial, and triennial screening interval. • Adherence and diagnostic yield of a first…
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Celecoxib, as a selective COX-2 inhibitor, has in vivo disease modifying activity in addition to its inflammation regulatory properties, in comparison to naproxen as a conventional non-selective NSAID.
The ICSI procedure interferes with the process of X chromosome inactivation in human embryos
MTP-soft tissue- release has a better outcome in correcting reumatoid MTP- deformities, compared to the Hoffman procedure
The goal of this study is to answer the following questions: 1. Is initiation of mechanical ventilation at home equally effective in improving gas exchange as compared to the initiation of it in the hospital? 2. Is initiation of mechanical…
1. At baseline, memory performance and neuroendocrine reactions are expected to differ between novice MDMA (< 10 ecstasy exposures) users and heavy/experienced MDMA users (>100 ecstasy exposures). It is hypothesized that heavy MDMA…
Showering shortly after application of Androgel does not negatively affect testosterone plasma levels.