177 results
To investigate whether increased aldosterone levels in obese individuals lead to impairment of microvascular function through reduction of NO-availability, and to establish the role of microvasculaire dysfunction in the pathogenesis of salt-…
The objective of the proposed experiments is to study the effect of lighting intensity and spectral composition (correlated colour temperature) on thermal comfort and thermo physiology. The obtained insights can be used to improve thermal comfort,…
To compare the digestion and absorption of micellar casein versus calcium-caseinate and sodium-caseinate with enzymatic cross-linking in healthy young men.
Primary Objective: To study the change on performance on executive function and memory function (as measured on Neurocart), after an active challenge with methylphenidate (monoaminergic) and galantamine (cholinergic), compared to placebo, in…
Primary Objective: To investigate whether exercise (Diabetes Bootcamp) induces a change in intestinal faecal microbiota (rise of butyrate-producing intestinal microbiota) related to improved glycaemic control (peripheral and hepatic insulin…
To investigate whether postprandial insulin release is affected by administration of the secundary BA DCA
The aim of this (pilot) study is to investigate if stress affects memory and attention skills by impacting the dopamine and noradrenalinesystem.
The primary objectives are to investigate whether L-carnitine infusion may rescue lipid-induced insulin resistance and whether L-carnitine infusion is improving metabolic flexibility in the state of lipid-induced insulin resistance. Furthermore,…
to investigate the analgesic effect of high frequency 10 Hz rTMS on experimental pain measured through quantitative sensory testing (QST) in healthy subjects.
18-22 YEAR OLD MALES WIHT A NORMAL WEIGHTExamine the possible attenuating cardiometabolic health effects of (A) hourly, 10-min standing interruptions, when compared to a single bout of prolonged sitting, and (B) sitting on a stability ball, when…
We hypothesize that formerly pre-eclamptic women have persistently increased angiotensin II sensitivity, sodium sensitivity, insulin resistance and sympathetic nerve activity together initially leading to susceptibility for early renal disease and…
In this study, we aim to investigate the difference in the anabolic postprandial bile acid response between an enteral and parenteral mixed meal test (MMT) in healthy lean men. This study is important because it may give a better understanding of…
Main aim; to show that NicVAX attenuates nicotine induced CNS effects on brain activation and cognitive performance relative to placebo. The secondary aim; to evaluate how these changes in CNS stimulation alter subjective measures and the addictive…
The aim of this study is to investigate the effect of a single bout of NMES on muscle protein synthesis rates in healthy elderly males.
This project aims to study how changes in serotonin alter interpersonal functioning in adults with or without a first degree family member diagnosed with MDD. The primary goal is to investigate the effect of experimentally lowered brain serotonin…
1. to study the effect of spironolacton and triamterene on blood pressure in anuric hemodialysis patients.2. to study the effect of treatment on body weight, serum elektrolytes, 24-hours sodium excretion, plasma aldosterone and renin concentrations…
Primary Objective: 1. Will an exposure to oxygen with a PO2 = 190 kPa lead to changes primarily in DLno compared to DLco?Secondary Objectives: 1. After an exposure to oxygen with a PO2 = 190 kPa for one hour, are the changes primarily located in the…
The aim of this study is to determine the immediate effects of oral alcohol consumption in healthy volunteers on gut wall integrity as measured by Intestinal Fatty Acid Binding Protein (I-FABP) and Lipopolysaccharide Binding Protein (LBP) These…
To study the effect of pectin in 5 different physicochemical states on ad libitum energy intake and possible underlying mechanisms; i.e. gastrointestinal hormones, gastric emptying rate, feelings of satiety and the method of fiber supplementation.
The primary objective of the biomarker study is to validate existing biomarkers for protein from dairy, meat, and grain/ legumes, and to identify new potential biomarkers for these types of protein in urine. Secondary objectives are 1) to establish…