87 results
To quantify muscle relaxation properties of fingerflexors using transcranial magnetic stimulation in patients with different myopathies to develop a screening diagnostic tool to assess who does (not) suffer from an underlying myopathy.
To evaluate the effects of intravenous iron suppletion in iron deficient PAH patients.Amendment: to compare exercise capacity and isolated muscle strength in IPAH patients and healthy controls
The primary objective of this study is to compare respiratory muscle strength values obtained using volitional techniques with values obtained using non-volitional techniques. The secondary objective is to compare the change for these two sets of…
Primary objective of this study is to assess the reliability, validity, and diagnostic value of the neuromechanical parameters of joint impedance estimated by nonlinear SIPE technology in patients with a spastic paresis.
To investigate the acceptability and feasibility of exercise therapy in an aquatic environment by patients after burn injury.
1. How does muscle overloading expressed by pain effect SB characteristics?2. What SB characteristics are associated with jaw-muscle pain?3. Are SB and psychological stress contributing factors for TMD pain?
PRIMARY OBJECTIVE1. To determine the contractile strength and the (ultra)structure of single diaphragm muscle fibers of mechanically ventilated patientsSECONDARY OBJECTIVE1. To determine whether diaphragm muscle fiber weakness is part of a…
Primary ObjectiveDifference in incidence of an avulsion injury and morphological changes of the levator ani muscle after a first normal vaginal delivery between participants with and without a mediolateral episiotomy.Secondary ObjectiveChanges in…
To develop non-invasive markers for tissue changes in skeletal muscle using MR methods
In recent studies physical training against resistance appeared to be the most successfull to prevent sarcopenia. Because of the bad physical condition of the elderly during a hospital admission resistancetraining can't be applied. A Pilot…
The objectives of this study are:1) to quantify the muscle symptoms, muscle complaints, limitations in daily living, fatigue, mood disorders, and quality of life in patients with Brody's syndrome.2) determining the genetic background of Brody…
The overall objective of the study is to quantify age-related changes in biomechanics and neural control of hand motor control and finger independence. Therefore, we will determine the finger interdependency during various finger tasks in terms of…
PRIMARY OBJECTIVE:To determine the contractile strength of diaphragm fibers of COPD patients before and after in vitro exposure to CK-107. SECONDARY OBJECTIVE:To determine the contractile strength of latissimus dorsi fibers of COPD patients before…
To investigate whether the CVS patients show the muscle membrane disturbances, as the FMS patients do. That is, are there muscle conduction velocities disturbances in the CVS patients?
To compare the oxygenation and oxidative metabolism in skeletal muscles of patients with CF with healthy controls to provide insight in the metabolism in patients with CF.
1) Determine the sarcomeric function in muscle fibers from FSHD patients2) Determine whether sarcomeric dysfunction is specific for FSHD or is part of a generalized pathology common to muscular dystrophies3) Test new therapeutic strategies (in vitro…
To fully characterize skeletal muscle strength and endurance, phenotype and muscle fiber type-specific satellite cell content in frail elderly as compared to those elderly that do not classify as frail according to clinical criteria.
In this study we want to investigate if relaxation time (RT) measured by handgrip myometry and muscle- elastography is a reliable outcome measurement for the quantification of myotonia in NDM patients. Mean RT values en standard deviations of NDM…
In this study we want to investigate if the muscle-relaxation time (muscle-RT), calculated from force profiles obtained with two different experimental methods (1) voluntary handgrip- and (2) peripheral nerve stimulation myometry, is a reliable and…
Primary Objectives:1: Gain insight in the way arm function changes during the natural course of DMD through 3D movement analysis, surface electromyography and ambulant activity monitoring.2: Investigate if a newly developed exoskeleton is able to…