760 results
Evaluate the patients experience and progression with robot assisted arm training exercises, and monitor changes over time on arm capacity tests and quality of movements that closely match daily tasks.
The primary objective of this study is to define and evaluate the clinimetric properties of the SMT in terms of validity and reliability.
To assess in vivo microglial activation (as a validated marker of neuroinflammation) using PET-CT and associated neuropsychological characteristics in patients recovered from sepsis associated delirium.
The objective of this study is to measure the stiffness of the elbow as a measure for axonal misrouting. This method can later aid physicians in determining whether to use botulinum A or not in OBPL.
The aim of this MRI study is to understand how neurodegeneration in MS (in vivo) is related to other facets of MS pathology, i.e. inflammatory (T2) lesions, black hole (T1) lesions, cortical lesions and damage of the normal appearing brain tissue.…
Measuring the thickness of the microvascular glycocalyx, and make a comparement between lacunar stroke patients and healthy controls.We also compare glycocalyx between patients with and without concomitant silent signs of cSVD on brain MRI.
The aim of this study is to investigate the differences between RLS and PLMS.
- Measurement of the flow response to dermal application of capsaicin in the trigeminal nerve region in women with and without migraine.- Measurement of the flow response to dermal application of capsaicin in the trigeminal nerve region at various…
• To investigate if FD in CRPS is associated with specific structural and functional changes of the brain.• If so, to find out which of these changes are specific for FD in CRPS, i.e., independent regardless the clinical setting (pain versus…
The primary objective of this study is to determine the prevalence and degree of impaired cerebral venous drainage in MS patients in comparison to healthy subjects.Secondly, we want to determine a possible relationship between the degree of impaired…
Identification of a diseased neuronal network characteristic in children with nocturnal epileptiform activity, which can explain language impairment in these children
Obtaining fundamental insight into sensorimotor integration in Parkinson's disease, targeted on (i) the relationship between cognitive deficits and prosodic anomalies, and (ii) the effect of music on the motor aspects of speech production.
Primary objective of the study: 1. To report on the age-dependency of the effect(s) of MPH or SSRI treatment on the outgrowth of the DA and 5-HT systems, respectively, using state-of-the-art Magnetic Resonance Imaging (MRI) techniques
The main point of this study is to detect in a controlled fashion if there is a relationship between CCSVI and MS. We focus on 5 parameters indicative of CCSVI: 1-reflux in the internal jugular vein (IJV) or in the vertebral vein (VV), or both with…
PrimaryTo investigate the inter-rater and intra-rater variability of a novel neurophysiological measurement (Motor Unit Number Index, MUNIX) for estimation of functioning motor units, in healthy controls and ALS patientsSecondaryTo evaluate the…
In the proposed project we aim to predict falls in daily life and to identify both aging- and disease-related impairments that underlie impaired postural control and an increased risk of falling in daily life.
This study should show whether patients with focal BG lesions are impaired in changing the threshold between deliberate fast or accurate conditions, and between conditions with and without prior information. Also, it should show that patients with a…
To develop pulse transit time into a diagnostic device which can be used to assess an altered cold/heat mediated vasomotor response (CHMV) (central component) and the flow-mediated dilatation (FMD) (peripheral component) in CRPS patients.
The goal of this study is to examine the effect of cooling on neuropathy in the hands of patients who are treated with Paclitaxel, Docetaxel en Oxaliplatin. Patients who will be included in the study are those who start with chemotherapy. The…
Primary objective: The ultimate goal is to achieve a more sensitive method for detecting malformations of cortical development. This encompasses two steps: the development of the method and the assessment of the sensitivity and specificity of the…