89 results
1. To compare the platelet function between healthy controls and patients with ET under both static and dynamic conditions. 2. To study the effects of anagrelide and hydroxyurea on platelet function. 3. To study the intrinsic platelet activation…
1. To establish whether serial exhaled breath analysis using eNose can detect invasive pulmonary aspergillosis in patients with prolonged chemotherapy induced neutropenia (neutrophil counts <0.5 x 10^9 for more than 7 days).2. To establish…
The primary objective in this observational study is to determine microcirculatory profile in preterm and term neonates. We would like to determine how the microcirculation changes in time during the phase of adaptation and correlate inter- and…
To characterise the different platelet activating pathways using the FACS assay and the different steps of primary hemostasis with a perfusion flow model in patients with hereditary thrombocytopathies; Storage Pool Disease (SPD), Glanzmann*s…
To investigate the functionality of the hemostatic system in patients at one year after OLT. Specifically, we will investigate the function of primary hemostasis (i.e., blood platelets), secondary hemostasis (i.e, the mechanisms responsible for…
Objective:The hypothesis of this study is that laboratory markers for blood coagulation, platelet activity and inflammation may help to identify patients at risk for a recurrent cardiovascular event after ACS. Secondary, we expect to find…
To investigate the in vitro effect of pro- and anticoagulants on the hemostatic capacity of plasma from patients with liver cirrhosis.
Primary Objective: The primary objective is to investigate the effect of hypoxia on blood coagulation using different techniques, among others the very sensitive TG assay in whole blood and plasma.Secondary Objective: The secondary objective is to…
This study evaluates if there is a difference in platelet function during and following the use of minimal ECC compared with conventional ECC in coronary artery bypass grafting (CABG) analysed with tromboelastography en multiple electrode aggrometry…
The main, primary objective of this study is identification of the molecular mechanisms that regulate structure and function of red blood cells in patients with neurodegeneration accompanied by the presence of abnormal red blood cells (…
- The primary research objective is to estimate the prognosis of children affected by ICL. - A secondary research objective is to explore the heredity of ICL between first degree family members.
To elucidate the pathogenetic mechanism of endothelial cell activation in DENV infected patients with sickle cell disorder.
We will study the effects of the proteins of the contact activation system in thrombus formation, embolization and degradation in several coagulation assays.
To sess the relationship between cerebral perfusion and clinical findings (neurological and neuropsychological) in patients with sickle cell disease.To compare iamging fincdings in children with and without sickle cell disease.
This observational cohort study is designed to evaluate the prevalence of acquired von Willebrand*s syndrome in patients with a new diagnosis of overt hypothyroidism.
The primary objective of this clinical controlled trial is to define the overall effect of adenocorticotropic hormone on coagulation parameters in patients with primary adrenal insufficiency (as diagnosed by their physician by previous short ACTH…
To study whether microcirculatory perfusion is improved by ECMO. Perfusion will be studied before & after ECMO start, during ECMO weaning and before & after ECMO stop. To study the precictive value of perfusion and its correlation…
to establish the accuracy with which the eNose can discriminate patients with invasive pulmonary aspergillosis from controls
To investigate the relation of platelet responsiveness and systemic platelet activity to phenotype in patients with severe hemophilia A.