162 results
To evaluate the effect of FICare in SFR on cognitive development at 5.5 years of age as measured by the WPPSI-IV in preterm infants hospitalised in a level-2 Neonatal Ward as compared to SNC in OBU To evaluate the effect of FICare in SFR on parental…
The primary aim of this study is to accurately compare the mid and long-term migration of two uncemented total knee prostheses. The secondary objectives of this study are to evaluate whether inducible displacement can be used as a parameter to…
Research question: Is maternal microbiome dysbiosis in MOB an underlying mechanism in the pathophysiology of adverse maternal pregnancy and offspring outcome?Objectives: Analyse the differences between the gut and vaginal microbiome, maternal and…
The primary objective of the second part of the study, which is the focus of this application, is to perform a comparative analysis of the cognitive profile and MRI outcomes of DMD/BMD patients.
The primary objective is to evaluate longitudinal developmental changes in brain structure in patients aged 6-18 years with SCD. The secondary objective is to analyze the longitudinal relations between biomarkers, demographic characteristics, brain…
The main objective of this study is to validate a simple screening tool and a best-practice assessment battery for the different components of HRPF against gold standard measures. Secondary objectives are to objectively assess the incidence of…
This study has been transitioned to CTIS with ID 2024-511115-25-00 check the CTIS register for the current data. Primary Objective:The primary objective of this study is:• To evaluate the efficacy of namilumab in subjects with chronic pulmonary…
The primary objective of this study is to determine the variation in postprandial glucose responses to the same meals/food products and how this relates to the variation in postprandial glucose responses over a 9-week fully controlled dietary…
Primary objective: To investigate baseline* left ventricle longitudinal strain rate values in a population of growth restricted fetuses and to compare these with a population of appropriate for gestational age fetuses.Secondary objective: To…
To investigate the effects of ICIs (anti-CTLA4, anti-PD1, combination anti-CTLA4/PD1) on vascular inflammation (PET-CT) in stage III melanoma patients. We hypothesize that the increase in vascular inflammation will be greater in the exposure group…
Het primaire doel is het bepalen van de sensitiviteit en specificiteit van de MR Pulmonalis Angiografie (MRPA) waarbij de CT Pulmonalis Angiografie (CTPA) de gouden standaard is.** Als secundaire uitkomsten: het bepalen wat de klinische…
Our main goal is to develop an in vitro model to investigate the function of wildtype and mutant KDM2B in neuronal development. We want to use this model to investigate genotype-phenotype correlations, elucidate isoform expression in neuronal…
Overall aimIdentify immunologic imbalances, with a focus on IFN, NETs, complement and lymphocyte subsets during pregnancy in women with systemic autoimmune diseases.HypothesisWe hypothesize that increased IFN activation and NET formation in patients…
The objective of the study is to assess the efficacy and costeffectiveness of eCAR in patients with MALS.
The aim of the here proposed study (BLOC-II) is to clarify whether cardiac function in survivors of BC should be monitored by GPs. We expect to clarify whether an unselected population of long-term BC survivors is at increased risk of developing…
To investigate the tolerability and effect of pure cafeine food suplement pre-administration on myocardial [18F]FDG uptake suppression.
We aim to further explore the role of decreased activity and stability of PK in several types of hereditary hemolytic anemia and non-regenerative anemia. Moreover, we will study the effect of restoring this instability using second generation (…
The aim of this project is to examine the association and interaction between environmental and genetic factors and development over time in adults with ASD. We examine if and how genetic and environmental factors might contribute to the course of…
The primary objective is to influence amygdala and ventral striatum neuronal activity, thereby changing their influence on consequent approach/avoidance decisions, as indicated with left or right button presses.
With this study, we aim to gain insight in the influence of dietary oxalate on urinary oxalate levels by quantification of the intestinal oxalate absorption in patients with recurrent idiopathic calcium oxalate stones, primary hyperoxaluria, and…