38 results
The purpose of this study is to investigate the value of postoperative cryotherapy on subjective patients-reported pain; shoulder function and quality of life in patients operated for SAPS .
Primary Objective: The primary aim of this study is to determine the degree of patient satisfaction and assess objectively the clinical outcome at a minimum of five years follow-up after surgical intervention. Secondary Objective(s): The secondary…
To investigate the pathophysiological link between RA and PD, and test the efficacy of RvE1 treatment in gingival tissue biopsies of RA-PD and RA risk-PD patients ex vivo.
PRIMARY OBJECTIVEThe primary objective of the study will be to determine the efficacy of 12 weeks of nilotinib treatment as measured by the non progression rate (Complete response + Partial Response + Stable disease according to Response Evaluation…
Open surgical treatment for calcified insertional Achilles tendinopathy; a long-term follow-up study
In this study we will assess the results of the operative treatment in the AMC using three questionnaires. In addition, to determine whether radiography is also useful as a diagnostic tool after a successful treatment, a conventional lateral…
1) To diagnose occurrence and details (form, size, location) of cyst formation or other MRI abnormalities in patients with Ceramic-on-Polyethylene bearings; 2) To correlate these findings to the clinical status of the patient; .
In this study we will evaluate the diagnostic value of ultrasound in patients presenting without clinical observable synovitis at firstconsultation compared to de clinical diagnosis by the rheumatologist in the 12 month follow-up of this study.
A pragmatic randomized single blinded clinical trial was designed with the objective to compare the use of customized insoles, night splints and a barefoot technology shoe for the treatment of plantar heel pain syndrome.
The objective of the study is to standardize portal placement in endoscopic calcaneoplasty, thereby taken into account the three different foot shapes, cavus, valgus and normal feet. Primarily the FOPP- device needs to be validated. If found valid,…
To get an impression concerning the patient flow, degree of patient drop-out, required time for the research workers, financial costs, logistical problems and the effectiveness of treatment with tape.
To evaluate the reproducibility of DCE-MRI measurement of the joints analyzed by color coded shape mapping, and by compartmental model analysis.
To collect synovial tissue and cartilage from patients with non-inflammatory joint diseases, that can be used in different studies as control for the evaluation of changes in RA synovial tissue, in order to gain more insight in the pathogenetic…
The main objective of the study was to prove the effectiveness of cryoablation in palliating pain and correlate the patients with a matched group of the Dutch bone metastasis study. The secondary objectives are to determine the accuracy of cryoprobe…
The primary aim of this study is to investigate if a tight multiple cardiovascular risk reduction program is effective in reducing progression of Intima media thickness progression (subclinical atherosclerosis) in patients with RA compared to usual…
Primary objective:To determine the hepcidin levels before, 2, 4, 8 and 24 hours after the administration of anti-IL-6R in patients with RA.Secondary objective:To determine the levels of Iron, transferrin , (calculation of transferrin saturation),…
-What are the testcharacteristics of an anti-CCP2 quicktest (sensitivity, specificity, positive and negative predictive value, kappa statististics) using capillary or venous blood compared to the golden standard, the anti-CCP2 Elisa in serum?-What…
The primary objective of this endpoint study is to evaluate the safety of tofacitinib at two doses versus TNFi; the co-primary endpoints are adjudicated major adverse cardiovascular events (MACE) and adjudicated malignancies excluding non-melanoma…
To obtain insight into the occurrence and nature of potential problems underlying difficult-to-treat RA and into its clinical burden, that will eventually be used to improve the management approach for difficult-to-treat RA.
To compare retrospectively reconstructed, radially sampled contrast-enhanced MR images of the liver with conventionally acquired contrast-enhanced MR images of the liver in terms of Quality of enhancement (QE), overall image quality (IQ), liver edge…
The objectives of this study are to evaluate the safety, efficacy, and pharmacokinetics (PK) of AMB-05X in the treatment of tenosynovial giant cell tumor (TGCT)