126 results
The study aims to determine whether fitness and daily physical activity determine fatigue in patients with IBD. Therefore we will examine whether there is a relationship between fitness, daily physical activity and fatigue in these patients. It will…
The first objective is to determine whether the routine use of endostaplers for closing the appendiceal stump will lead to a lower incidence of infectious complications (intra-abdominal abscess, wound infection), compared to loop closure. The second…
To evaluate the presence of anatomical changes in painful joints in IBD patients with a dedicated peripheral extremity MR scanner.
Hypothetically, in patients with PBC or PSC the FGF-19 production or -response could be altered. The goal of this research is to study the FGF19 production after a standardized oral fat challenge and the effect of this FGF19 production on bile acid…
To study potential abnormal functioning of the bile salt-FXR-FGF19 axis in patients with clinically quiescent Crohn*s colitis.
To investigate if endoscopic transgastric necrosectomy will lead to a reduction ofthe per- and postoperative pro-inflammatory response, as compared to necrosectomy by laparotomy, in patients with infected (peri-)pancreatic necrosis.
Systematic gathering of biomaterial and phenotypic data of IBD patients during clinical care provides assessment of molecular markers in the DNA, the transcriptome and proteome. The markers can be associated with the different disease phenotypes and…
Study of the cost-effectiveness of fatigue management in patients with Crohn*s disease (CD) and Ulcerative Colitis (UC)
Assesment of small bowel CD activity using the NBI compared to the conventional white light endoscopy, using the single balloon enteroscopy system in patients with known CD and suspected small bowel disease activity.
To demonstrate and compare expression of CCL25 and CCR9+ lymphocytes in peripheral blood and colon of PSC-, PSC/IBD-, IBD-, gastroenteritis patients and controls.
The present study aims to investigate genetic factors that contribute to the development of BE.
The current project aims to confirm this defective production of IL-8 and explore the possible underlying defect by examining the functionality of the major signal transduction pathways involved in IL-8 production.
Primary objectiveTo define a parameter, or parameters, in peritoneal drain fluid that have diagnostic value for clinically manifest anastomotic leakage of a colorectal anastomosis in the early postoperative period.Secondary objectivesTo compare the…
To compare endoscopic pancreatic fluid collection drainage using a standard oblique-viewing US endoscope versus a prototype forward viewing ultrasonic endoscope with emphasis on ease of endoscopic drainage measured by procedural time.
Aim:With this study we would like to prove that also in humans, NOD2 signaling inhibits the TLR2-mediated immune response.
Aim of this study is to investigate the efficacy of *precision dosing* IFX maintenance treatment in comparison with standard IFX maintenance treatment in IBD patients in clinical remission.
The objective of this registry is to obtain long-term safety and clinical statusinformation on pediatric patients with IBD (ie, CD, UC, or IC).
Multiple sensitizations were found using allergy tests, but most of the EoE patients have concurrent allergic diseases and the specific IgE found in serum apparently does not play a role in EoE pathogenesis. This theory is supported by the failure…
Primary objective:- To demonstrate that CT-P13 is noninferior to Remicade at Week 6 (Dose 3), in terms of efficacy, asdetermined by the Crohn*s Disease Activity Index (CDAI)-70 response rate.Secondary objectives:-To evaluate long-term secondary…
The objective is to investigate the correlation between bacterial/viral gut infections and acute appendicitis in children.