27 results
Concordance between MET diagnosis with and without the use of ultrasound with the chart review definitive diagnosis will be studied. Also other secondary endpoints will be evaluated.
To assess the potential of a short neuropsychological test measuring attentional variability and vigilance preoperatively in predicting postoperative delirium among elderly non-dementia patients undergoing elective surgery.
To assess the safety and feasibility of inducing mild hypothermia prior to reperfusion as a means of reducinginfarct size in subjects suffering from STEMI and improve neurologic outcome in subjects experiencing CA followingthe return of spontaneous…
- to determine possible differences in the results of the ABILHAND kids questionnaire between parent, occupational therapist and rehabilitation doctor- variance of the results in time
To evaluate the course of concentrations of oxidative stress parameters and neuro-biomarkers in cord blood, serum and urine of full-term asphyxiated neonates. Furthermore, to investigate whether these concentrations are correlated to hypoxic…
Hereto, the project wants to meet the following goals:1. To produce an EEG instrument for continuous brain monitoring, the NeoGuard, enabling automated detection of neonatal seizures and abnormalities in the EEG background pattern. The neonatal…
To evaluate the prognostic value of the EEG, including quantitative EEG features, TMS and SSEP after out-of-hospital cardiac arrest.
Study (population) pharmacokinetics of midazolam, morphine, phenobarbital and lidocaïne during therapeutic hypothermia for adequate dose adjustments.
To determine the effect of the application of burn dressings on the skin of face and neck on the tympanic temperature of healthy volunteers.
Goals• Increase the knowledge of the Pgp in the pathophysiology of Alzheimer's disease. • Designing an in vivo method, by positron emssion tomography, for measuring Pgp function and Aβ concentration to possibly determine the risk of converting…
The objective of this study is to develop an effective behavioural treatment for severe drooling. The hypotheses are:1. A behavioural program containing instruction, goal setting, positive practice, self-management techniques, and positive and…
Primary objective is to assess in vivo neuroinflammation quantitatively in patients with sepsis. Secondary objective is to study whether differences in in vivo neuroinflammation are related to long term cognitive outcomes.
Our aims are to identify the clusters of impairments in cognition, behavior, quality of life, and fatigue in children after anti-NMDAR encephalitis, to identify risk factors affecting functional outcome and to assess the progression or remission…
Primary Objective: to determine the strength of the dynamic autoregulation of patients after cardiac arrest during the post cardiac arrest syndrome. Secondary Objectives:to observe the natural course of the autoregulation during the first year after…
Primary objective is to quantitatively assess differences in in vivo neuroinflammation in patients before and after coronary artery bypass grafting (CABG) surgery. Secondary objective is to study whether diffferences in in vivo neuroinflammation are…
1. To estimate the additional value of early MRI monitoring for the prediction of neurological outcome of comatose patients after cardiac arrest. 2. To gain insight in the pathophysiology of PAE by functional MRI measures and by associating MRI…
Using single-cell transcriptomic and epigenetic profiles of (immune) cells in liquor to investigate which biological and cellular processes are involved in (accelerated) brain aging and cognitive decline after systemic inflammation.
To determine the potential impact of ball heading in football on brain integrity as assessed by blood biomarkers for neural damage in a real-world setting.
This study has been transitioned to CTIS with ID 2024-515128-35-00 check the CTIS register for the current data. The primary objective is:• To evaluate the safety and tolerability of a single local i.c. dose of SI-053 to establish the MTD and/or the…