40 results
To investigate lesion detection in patients with liver metastases of colorectal cancer with [18F] FLT-PET compared to CT at baseline (= gold standard). This investigation will be done based on a qualitative assessment of the scans ([18F] FLT-PET and…
Evaluate the safety and effectiveness of four cementless Taperloc versions: Taperloc Complete Reduced Distal and Taperloc Legacy Full Profile Reduced Distal compared to Taperloc Complete Full Profile and Taperloc Legacy Full Profile in primary THA.
To investigate the long term stability (> 5 yrs) in patients treated with mandibular distraction osteogenesis (MDO) for correction of a Class II-occlusion. Hypotheses:1) MDO is a technique for mandibular lengthening with comparable stability…
To evaluate whether no utilization of compressive stockings is as effective as wearing a Class II Thrombo Embolic Deterrent (TED) stocking for 4 hours. Primary outcome is leg volume on post-operative day 14.The secondary objective is to study the…
To test the cost-effectiveness of the psycho-educational intervention HypoBewust (HB) compared to care as usual.Research questions:1) Does HB significantly improve a) health related outcomes and b) societal costs after 6 months?2) Are the expected…
To assess the effect of an infant formula with an optimized amino acid composition and a lower total protein content during the first four months of life on infant growth. Amendment follow-up study: To assess the long term effect of the intake of an…
In the Netherlands, TEE is currently not used in emergency departments during cardiac arrest. The purpose of this study is to investigate if point-of-care TEE can be used effectively and safely in patients with cardiac arrest.
The main objective is to determine genetic phenotype and the prevalence of anti-HLA (human leucocyte antigen) and anti-HPA (human platelet antigen) antibodies in patients with Glanzmann thrombasthenia.
The aim of the current study is to 1) investigate what the effects are of a condensed, intensive outpatient exposure treatment in patients with OCD who are not sufficiently improved from standard CBT (ERP) and 2) to map early indicators regarding…
To determine safety, tolerability, and activity of individualized radioembolization with 166Ho-microspheres combined with FTD-TPI and bevacizumab.
To quantify how much a full-time brace corrects the spine in 3D in AIS patients when supine, compared to a dedicated night-time brace.
Collecting blood samples of healthy volunteers (n=650) which can serve as a reference for the Personalized Parkinson Project.
Define reference values for gastric and oesophageal scintigraphy for post-bariatric surgery patients.
The primary objective:To identify fluid and radiological biomarkers, in IA carriers, AHD patients, and EoHD patients, that can be linked to clinical outcome measures. We aim to link longitudinal changes in these biomarkers to disease progression.…
The primary objective of this clinical feasibility study is to assess the overall diagnostic yield of the Investigational Device in comparison to standard care. The secondary objective is to assess the safety issues that possibly occur while using…
IVD1: The primary objective of this clinical performance study is to evaluate the effectiveness of the MyChoice® test in identifying HRRm or non-HRRm mCSPC patients as part of the enrolment criteria for EvoPAR-prostate01. This clinical performance…
Investigating the function of monocytes and their precursor cells originating from circulation, bone marrow, and spleen in the context of ovarian cancer.
Primary objectives: 1.1) To investigate to what extent the different functions of the cerebral microvasculature are impaired in type 1 diabetes; and 1.2) To investigate to what extent the different functions of the cerebral microvasculature are…
The main objective of this study is to demonstrate treatment efficacy of MR-HIFU ablation of breast cancer. Effective treatment is defined as 100% necrosis of the targeted primary breast tumor. The secondary objective is safety of the MR-HIFU…
To assess the impact on treatment decision of a screening MRI brain in asymptomatic patients with newly diagnosed stage IV non-oncogene addicted NSCLC, fit for systemic treatment.