37 results
The aim of this study is to combine acoustic characteristics from spontaneous speech and results from tests at different linguistic levels e.g. the Diagnostic Instrument for Mild Aphasia (DIMA), to determine which aspects in speech are most…
To assess the efficacy of early mechanical left ventricular unloading and standard of care (inotropes/vasopressors) versus inotropes/vasopressors alone (standard-of-care) in patients with ADHF and signs of cardiogenic shock.
This study has been transitioned to CTIS with ID 2024-512639-58-00 check the CTIS register for the current data. ____________________PRIMARY OBJECTIVESFor Parts 1 and 2: To assess the safety and tolerability of BNT142 at all dose …
To compare the effectiveness of a generalist approach (GIT-PD) to specialized psychotherapy for personality disorders (PD) and to predict for which individual patient generalist treatment is not inferior to specialist treatment.
the primary aim is to determine the effect of thawed deep-frozen platelets re-suspended in thawed deep-frozen plasma versus room temperature stored platelets in platelet additive solution for transfusion on the percentage of patients with surgical…
Objective 1: The LifeMeds cohort aims to longitudinally identify characteristics of individuals with multimorbidity (at least two of the following chronic diseases: CVD, CRDs,T2DM and/or cancer), including lifestyle behavior and its determinants. 1a…
The primary objective of this study is to assess the safety and performance of the ABLE Daily to perform ambulatory functions in home and community settings for people with spinal cord injury.The secondary objectives are to assess the impact of the…
Primary objective: To assess the feasibility of donor screening, collection, production and storage of sufficient CB-RBC products to potentially meet the transfusion need in extremely preterm neonates.
1, Quantify and compare vascular and structural parameters obtained from AO-FIO, OCTA, OCT, and CFP in both healthy controls and glaucoma patients; 2, Investigate the correlation between these parameters and assess the additional value of vascular…
The overall aim of the Ageinglines cohort study is to better understand the biological ageing process and its association with the onset (pre)frailty and well-being in later life and to identify targets for delaying the biological ageing process…
to determine if freedom of AF may be improved by delivering more, and targeted PFA applications while avoiding side-effects of higher PFA dosing.
The aim of this study is to compare the efficacy and safety of preoperatively placed Pericapsular Nerve Group block (PENG), Fascia-Iliaca Compartment Block (FICB) and Femoral Nerve Block (FNB) for patients with hip fractures in the ED.
To assess the adherence to the intervention regarding successfully followed exercise sessions, adverse events related to the intervention and experiences of intervention supervisors and participants. Secondly, we will evaluate intervention effects…
Primary objective:What is the incidence of an unsafe swallow situation (PAS score >= 6) after decannulation in ICU patients who had a safe swallow situation with a tracheal cannula prior to decannulation (PAS score < 6)?Secondary…
Primary Objective: Assess which digital health metrics are relevant to monitor for patients with (or highly suspected of having) obstructive sleep apnea before and after diagnosis, and during titration of treatment with continuous positive airway…
The overall aim of this study is to identify and describe distinct recovery trajectories with the innovative digital resilience assessment tool (Orion) in older oncology patients and patients with stage IV lung cancer during systemic therapy.
This study aims to evaluate A-mode ultrasound for assessing JVPW characteristics as a non-invasive tool to discriminate between healthy subjects and those with pulmonary arterial hypertension patients, and to assess if JVPW changes relate to changes…
The primary objective is to evaluate the feasibility of ICG-enhanced near-infrared qFME to determine tumour demarcation and tumour depth in upper GI tumours (e.g. HGD or superficial oesophageal and/or gastric adenocarcinoma (T1)) during ESD.
The REPLACE study aims to determine whether not changing the catheter (catheter retained) for catheter-associated urinary tract infections (CAUTI)affects the recurrence-risk of CAUTI.
To explore whether vigorous endurance exercise (i.e., running a marathon) alters the magnitude of cardiac damage following myocardial ischemia-reperfusion injury in amateur athletes through using an ex vivo rat heart model of myocardial infarction.