37 results
1. Immunology and Pathology:To determine the immune response of patients with simple and complex appendicitis in order to identify markers which distinguish between simple and complex appendicitis.2.Clinical and Imaging:To analyze the differences in…
The primary objective is to study the effects of the inflammatory response to a surgical procedure on postoperative cognitive decline in elderly cancer patients and to compare this to the effects of the inflammatory response on postoperative…
To directly evaluate the gastric tube microcirculation with Dark Sidestream imaging during minimal invasive esophageal resection on several locations, i.e. from best arterial blood supply (antrum) to worst (fundus). Furthermore, to evaluate the…
Primary objective is to evaluate the use of deep muscle relaxation versus on indication only on surgical and anesthesia conditions in patients for endoscopic esophageal resection.Secondary objective is to evaluate the (hypothetical) dose of…
In this study the effect of the pneumoperitoneum on the intestine of children is objectified by measuring the iFABP levels in the urine, as an indicator for the ischemia or damage to the intestine. To exclude any iFABP increase due to intestinal…
To identify predictive variables correlated with percentage excess weight loss, reversal of metabolic complications of obesity and quality of life and postoperative complications; to identify metabolic variables correlated with markers of the…
In this pilot study experience will be obtained in diagnosing POCD and its risk factors, in elderly surgical cancer patients.
To determine whether surgery induces changes in the liver vasculature of patients with colorectal cancer.
To identify circulating mediators that are released after surgery and which are responsible for macrophage activation.
The primary objective to our study is assessing functional outcome, quality of life, and genetic mutations in patients with a cloacal malformation. Functional outcome:- Colorectal functiono Objective: assessing colorectal function through the use of…
We propose to perform a pilot study to examine the feasibility of studying the triangular association between: 1) amino acid metabolism (influenced by, amongst other factors, diet composition [e.g. energy intake, macronutrient intake, individual…
The primary objective of the study is to assess (acute) brain injury in the perioperative phase by cerebral MRI in infants with non-cardiac congenital anomalies requiring surgery in the neonatal period.
To determine if the microbiota inhabiting the small intestine in morbidly obese patients with T2DM is comparable to those without T2DM and, if not, what are the deviations and what is their impact
The primary objective is to examine the predictive value of several types of endogenous inhibitory functions for the risk and severity of acute and persistent pain after surgery. As primary outcome parameter, patients will be asked to keep a pain…
1) To investigate what changes are present in skeletal muscle tissue of elderly gastric and colonic cancer patients (>80) compared with younger gastric and colonic cancer patients (<60) and compared to elderly controls and younger…
We hypothesize a lung*protective mechanical ventilation using lower tidal volumes during general anesthesia for minimally invasive transthoracic esophagectomy to protect against postoperative pulmonary complications in patients undergoing minimally…
To investigate whether local inflammation in the area of the stomach and gastroenteric anastomosis is a cause of primary DGE.
To investigate the feasibility and safety of a diet containing 30% caloric and 70% protein restriction given during five days in healthy kidney donors planned to undergo a live kidney donation as well as persons awaiting bariatric surgery.…
The feasibility of preparing untreated esophageal adenocarcinoma endoscopic biopsies towards DNA/RNA samples suitable for next-generation sequencing.
This study will be performed to evaluate the effectiveness of the EndoBarrier device for the treatment of obesity 3 years after surgery.