64 results
We will investigate the effect of the combination of moderate physical activity and a standard meal on the onset of low grade intestinal ischemia. Will will use the serological biomarker I-FABP to determine the occurrence of low grade intestinal…
To investigate the impact of (a disrupted) circadian rhythm on food preferences and chemosensory perception.
Aim of this pilot study is to determine which intervention groups are feasible in a larger trial which aims to a compare postoperative pain and complication rates in moderate versus deep neuromuscular blockade, and normal versus low intra-abdominal…
To determine the effect of gastric bypass surgery on (alterations in) food preferences. Secondly, to assess the effect of gastric bypass surgery on the brain reward response when exposed to sight and smell of food stimuli with different sugar and…
To determine whether pulmonary rehabilitation prior to bariatric surgery leads to improved and sustained asthma control (ACQ) as compared to bariatric surgery alone in patients with morbid obesity and not optimally controlled asthma.Secondary aims…
The primary objective of this study is to assess if cannabinoids modulate sweet taste intensity and liking.
In this study, we want to investigate whether obese children perform differently than normal weight children (data already generated) on tasks of sensitivity to reward and executive functioning.
To demonstrate differences in neuronal structure and neuronal function in brain regions that control eating behaviour between obese and normal weight adolescents.
We propose that there will be a link between taste sensitivity and overall metabolic function. We hypothesize that non-tasters, medium-tasters and super-tasters will have different levels of metabolic hormones in their general circulation. Our study…
The aim of this study is to assess differences between lean and morbidly obese subjects in gut permeability, gut microbiota and mucosal inflammation and to assess the effects of weight loss after sleeve gastrectomy on gut permeability, microbiota…
The purpose of the proposed research is to investigate which patients may report less weight loss and worse quality of life in the first two years after a gastric bypass operation. Moreover, the proposed study will offer information why and when…
Objective: To study differences of (adipo) cytokine spectra in visceral and peripheral adipose tissue and to study the effect of caloric restriction on (adipo) cytokine production of these different fat tissues.
The objective of the first part of the study is to assess whether circadian misalignment: - decreases energy expenditure and activity induced energy expenditure - alters substrate oxidation- alters feelings of hunger and satiety - alters food choice…
Hypotheses: - The nutrient sensing receptors have a different spatial distribution along the intestinal tract.- The receptors: T1R2/T1R3, SGLT-1, G-protein coupled receptor 120, T1R1/T1R3, Pept1, G-protein coupled receptor 93, calcium sensing…
1) Examining actual changes in food intake and food preference for different foods following psychosocial laboratory-induced stress;2) Examining the effect of multiple (instead of single) dietary TRP administration on acute stress-induced (negative…
To study the effect of early tumour development on brown adipose tissue activity
Primary Objective: To study the effect of VNS on BAT activity.Secondary Objective(s): Measure the effect of VNS on energy expenditure, core temperature, skin surface temperature and skin perfusion during active and absent stimulation.Follow the…
To study the effect of thyroid hormone and thyroid-stimulating hormone on brown adipose tissue activity.
We propose to perform a pilot study to examine the feasibility of studying the triangular association between: 1) amino acid metabolism (influenced by, amongst other factors, diet composition [e.g. energy intake, macronutrient intake, individual…
To determine if the microbiota inhabiting the small intestine in morbidly obese patients with T2DM is comparable to those without T2DM and, if not, what are the deviations and what is their impact