50 results
Primary objective:The following hypothesis will be tested:MuSSAP in infants 4-12 months of age with diagnosed unilateral cerebral damage, is a feasible protocol and results in an enhanced motor development as compared to Intensive Usual Care (Upper…
Concordance between MET diagnosis with and without the use of ultrasound with the chart review definitive diagnosis will be studied. Also other secondary endpoints will be evaluated.
The primary objectives of this study are:* To evaluate tracer kinetic models for the purpose of quantifying specific binding of 18F-AV-1451 in cross sectional and longitudinal applications; and* To evaluate simplified methods for quantification of…
Are changes in cognitive functioning related to structural changes in the brain in patients with type 1 diabetes mellitus. How are these changes related to diabetic complications like duration of chronic hypoglycaemia, disease duration and presence…
To assess the potential of a short neuropsychological test measuring attentional variability and vigilance preoperatively in predicting postoperative delirium among elderly non-dementia patients undergoing elective surgery.
To assess the safety and feasibility of inducing mild hypothermia prior to reperfusion as a means of reducinginfarct size in subjects suffering from STEMI and improve neurologic outcome in subjects experiencing CA followingthe return of spontaneous…
- to determine possible differences in the results of the ABILHAND kids questionnaire between parent, occupational therapist and rehabilitation doctor- variance of the results in time
To evaluate the course of concentrations of oxidative stress parameters and neuro-biomarkers in cord blood, serum and urine of full-term asphyxiated neonates. Furthermore, to investigate whether these concentrations are correlated to hypoxic…
Hereto, the project wants to meet the following goals:1. To produce an EEG instrument for continuous brain monitoring, the NeoGuard, enabling automated detection of neonatal seizures and abnormalities in the EEG background pattern. The neonatal…
Primary objective: To evaluate whether there is a difference in all-cause mortality at 180 days or longer with a target temperature management at 33°C compared to a target temperature of 36°C, in patients unconscious after out-of-hospital OHCA.…
Primary Objective: 1) To charaterize microbleeds and microinfarcts at 7T, and compare their prevalence in people with and without diabetes, with or without cognitive impairmentSecondary Objective(s): 2) To assess the relevance of the lesions in the…
Primary Objective: 1) To compare the prevalence en number of microbleeds at 7T between older people with and without DM2, and to relate the lesions to cognitive performanceSecondary Objective(s): 1) To characterize cerebral microinfarcts at 7T and…
To evaluate the prognostic value of the EEG, including quantitative EEG features, TMS and SSEP after out-of-hospital cardiac arrest.
Study (population) pharmacokinetics of midazolam, morphine, phenobarbital and lidocaïne during therapeutic hypothermia for adequate dose adjustments.
To determine the effect of the application of burn dressings on the skin of face and neck on the tympanic temperature of healthy volunteers.
Goals• Increase the knowledge of the Pgp in the pathophysiology of Alzheimer's disease. • Designing an in vivo method, by positron emssion tomography, for measuring Pgp function and Aβ concentration to possibly determine the risk of converting…
The development of an attractive child centred intervention based on the forced use perspective, to study the effects regarding the following question:Is a period of 6 weeks Forced Use of the more affected upper limb (I) for children with Cerebral…
To assess if the studied TCD variables of cerebral autoregulation and hemodynamics are abnormal during preeclampsia. And if so, to determine if these changes are large enough to have potential value to determine a threatening cerebral dysfunction in…
The main objective of the study is to acquire more insight in memory for emotional information in patients with Alzheimer*s Disease, compared to healthy elderly people. A second objective is to explore the effect of emotional content on working…
The objective of this study is to develop an effective behavioural treatment for severe drooling. The hypotheses are:1. A behavioural program containing instruction, goal setting, positive practice, self-management techniques, and positive and…