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Misoprostol in the management of retained placenta, a safe alternative for manual removal? A randomised controlled trial

To assess the effectiveness of misoprostol in the management of retained placenta. Will 800 micrograms of misoprostol orally reduce the need for manual removal under general anaesthesia and prove to be a safe alternative?

Patients' view on the prevention of preterm birth (Preventing preterm birth in women with a previous preterm birth: identification of obstacles to change)

The aim of this study is to identify factors that can hamper of facilitate the implementation and to use this knowledge to develop an effective implementation strategy.

Volumetry during the first trimester of the pregnancy using three-dimensional ultrasonography

Understanding the normal development of the early pregnancy and observing this process ultrasonographically has allowed us to monitor effectively first trimester pregnancy, and recognize early signs of abnormal outcome. The CRL (Crown-Rump-Length)…

A comparison of pethidine/meperidine intramusculary and remifentanil patient-controlled analgesia during labor in Westfriesgasthuis

The following hypotheses will be tested:Hypothese a: Remifentanil PCA gives a better labour satisfaction than pethidine/meperidine i.m.Hypothese b: Remifentanil PCA gives a better pain-relief during labour, than pethidine/meperidine intramuscularly.…

The Impact of Psychological and Medical Factors of Women having a Child with a Congenital Anatomical Malformation on Subsequent Pregnancy Decision-Making: a psychological evaluation.

To identify factors that have an influence on the reproductive decision-making for a subsequent pregnancy of women having a child with congential anatomical anomalies.

The Eindhoven Breech Intervention Study (EBIS)

Primary outcome is to evaluate whether successful ECV is associated with maternal thyroid function and mood state in single pregnant women with breech position at end term.

Correlation and level of agreement between echocardiography and a new inert gas rebreathing technique in estimating cardiac output

We would like to perform a study in which first the level of agreement and the correlation between echocardiography and the new rebreathing technique in estimating cardiac output will be determined.

Brain development after prenatal growth retardation; effects of growth hormone treatment

Whether cognitive functions in SGA children are impaired due to inappropriate developmental outgrowth in children born with a low birth weight is unknown. This is also the case for the fact whether GH treatment from the age of 4 years is still…

A comparison of remifentanil patient-controlled analgesia with epidural analgesia during labor

The main objective of this study is compare the analgesic efficacy and safety of remifentanil, administered as patient-controlled analgesia (PCA), with epidural analgesia.

The prevalence of postpartum posttraumatic stress symptoms, depression, anxiety and the need of control in women delivered in The Netherlands

To assess the prevalence of postpartum posttraumatic stress symptoms, depression, anxiety and the need of control in women delivered in The netherlands.

Endothelial dysfunction and pregnancy complications in women with congenital heart disease: an addendum to the ZAHARA-II study (ZAHARED study)

Primary Objectives: To prospectively investigate the changes in cardiac parameters (echocardiography, NT-pro-BNP) and uteroplacental flow (pulsatility index, diastolic notching) during/after pregnancy in women with CHD and compare these changes with…

Obesity as a risk factor during pregnancy

The objective of this study is to test the hypothesis that healthy obese pregnant women at increased risk for obesity-related pregnancy complications can be identified by a subgroup-specific screening program at twelve weeks amenorrhea.

Predictors for chronification of pregnancy related pelvic girdle pain.

To identify the factors who are responsible for the chronification of pregnancy related pelvic girdle pain.

SCAR study
Sonohysterographic evaluation of caesarean scar defects and determination of risk factors

Determination of the incidence of a scar defect .Determination of riskfactors for develpment of scar defects

Epidural analgesia versus Remifentanil PCA during labour

To compare Remifentanil PCA with epidural anesthesia among healthy nulligravidia during labor.