50 results
1). To compare temporal fluctuations of lung function and inflammatory biomarkers in blood, nasal lavage, exhaled air and urine between patients with asthma and controls.2). To investigate the change in variations of these biomarkers upon…
pagina 7-8 protocol
To assess the prevalence of BHD among patients with spontaneous sporadic and familial pneumothorax.
To validate two less complex techniques, electrical activity of the diaphragm and ultrasound of the diaphragm, compared to the gold standard (transdiaphragmatic pressures) for monitoring diaphragm function and inspiratory effort during assisted MV…
Primary Objective: To study the differences between EB post oxygen-dive, post air-dive (control), dry-dive (recompression chamber) and pre-dive (baseline).1. Will an exposure to a PO2 of 190 kPa (100% oxygen at 9 msw) during 60 minutes in an…
The main objective of this study is to assess the effects of rituximab (RTX) as a rescue therapy for therapy resistant progressive IMID- IP patients. Specifically there is an objective assessment of (1) pulmonary function tests (PFTs) and (2)…
The main objective of this study is to assess the effects of rituximab (RTX) as a rescue therapy for therapy resistant progressive IMID- IP patients. Specifically there is an objective assessment of (1) pulmonary function tests (PFTs) and (2)…
To optimize ventilator support in critically ill patients admitted to the intensive care unit by monitoring electromyography of the respiratory muscles.
The specific objectives are:1. What is the difference of in vitro CFTR function in CF patients with either mild (compound heterozygote A455E) mutations or severe (homozygote F508del) mutations with mild or severe clinical disease? 2. What is the…
The primary objective is to identify biomarkers measured in donor and recipient blood before lung transplantation which can predict lung graft function after lung transplantation. When the risk of PGD can be predicted, more adequate therapy can be…
Our longstanding goal is to assess the clinical applicability of EIT in intubated and mechanically ventilated patients. We aim to observe changes in regional lung ventilation during alterations of mechanical ventilation strategies in clinical…
Our longstanding goal is to assess the clinical applicability and technical feasibility of EIT in mechanically ventilated critically ill patients with acute lung injury. Our aim is to establish changes in regional lung aeration with EIT during…
Part I of the study: I) to determine if one or a batch of aging marker(s) is/are associated with the presence of objectively diagnosed COPD related co-morbidity (muscle wasting, osteoporosis, cardiovascular risk, glucose intolerance, renal failure,…
In this study we will provide reference values using the single occlusion technique in healthy infants aged 2 months - 1 year.
Primary Objectives: 1. Is it feasible to visualize active inflammation in patients with pulmonary sarcoidosis by using Diffusion Weighted Imaging when compared to 18F-FDG PET?Secondary Objectives: 1. Is it feasible to visualize lymph node…
The objective of this study is to assess changes in lung aeration and lung perfusion in patients who will undergo electrocardioversion.
Goals1. To investigate whether analysis of antibodies directed against active Beta1 and Beta 2-integrins (CD29/CD18) and FcγRII (CD32) of primed eosinophils allows the diagnosis of eosinophilic asthma as compared to analysis of sputum eosinophilia.…
Primary objective: to assess the correlation and agreement between the new TB technique and the conventional SB online technique with constant expiratory flow.Secondary objective: to investigate the reproducibility of this new technique.
Primary Objective:To determine breathprint variation of intubated and mechanically ventilated patients planned for elective surgery.Secondary Objective(s):Correlation between breathprints and (1) oxygenation, (2) biological markers of oxidative…
The study is a diagnostic study for the diagnostics of sarcoidosis, in where a new, endo-sonographic procedure is compared to the current, bronchoscopic method.The objective is to assess the accuracy, safety and patient tolerance of endo-sonography…