80 results
Assess amyloid beta clearance from CSF to serum in response to HFCWO in healthy volunteers:- Change from baseline in amyloid beta 40 (ng/ml) in CSFAssess endogenous protein biomarker clearance from CSF to serum in response to HFCWO in healthy…
Investigation of the performance of the Virax Immune COVID-19 kit when tested using blood donations from healthy participants.
Primary Objective: To test the feasibility of online neuropsychological assessments using the Amsterdam Cognition Scan (ACS) compared to classical neuropsychological assessments in patients with cancers with CNS involvement.
In the current study we aim to measure the postprandial amino acid uptake kinetics of barley rice protein, and compare this to pea protein. A benchmark protein (whey) will be included for comparability of amino acid uptake of different protein…
Primary objective 1) To evaluate the usability of the total viQtor solution applied and used 24/7 in clinical practice.This includes the ease of use and/or usability of:the wearable, charger and armband by the primary participants/usersthe *care…
To compare the appearance of dietary protein-derived amino acids in plasma after ingestion of a milk protein powder with different levels of protein glycation in healthy young men.
Individualized trajectories of upper arm disease progression in Duchenne muscular dystrophy patients
Main objective1. To assess the longitudinal trajectories of upper arm flexor muscle MRI parameters, muscle force and upper arm function in a cohort of ambulant and non-ambulant DMD patients, to assess the value of this muscle as target for…
The objective of this study is to assess the prognostic value of early perfusion changes and infarct evolution detected with magnetic resonance imaging (MRI) acquired directly after EVT.
The primary objective of this study is to investigate whether the use of the EOS calculator safely reduces antibiotic exposure in newborns with suspected EOS in the first 24 hours after birth compared to the current Dutch guidelines.Secondary…
The primary objective is to develop a disease model predicting clinical meaningful changes based on a combination of results of tests on clinical function, muscle MRI, echocardiography and circulating biomarkers applicable in various stages of…
Primary Objective: We aim to provide a clear phenotype of the immune system in patients with FOXP1 syndrome. Secondary Objectives:We aim to correlate the immunophenotype of patients with FOXP1 syndrome with frequency and type of infections reported…
Our main objective is to investigate the feasibility and cognitive effects of applying self-regulation strategies learned from large-scale brain network balance neurofeedback training on active memory suppression in a PTSD patient population.
The primary objective of the study is to predict the effect of a given ecological momentary intervention (either ReApp or Imager) based on acquired baseline measures. Further, the use of DBMs to generate an objective stressor reactivity score is…
This research aims to generate knowledge about the sexual experience of clients with an SMI. Possibly the acquired knowledge can be used to create awareness among care providers. The ultimate wish is to adapt the treatment to the sexual experience…
The primary objective of the study is to demonstrate the specific involvement of the cerebellum in reversal learning. The secondary objective is to investigate whether the behavioural effects of cerebellar cTBS on reversal learning are moderated by…
This study has multiple purposes:Primary objective:1: to investigate whether it is possible to identify the small mimic muscles independently of each other and to determine the exact position of the origin and insertion of the mimic muscles on 7…
To determine changes in brain activity in responses to the ingestion of flavored waters sweetened with either the nutritive sugar sucrose or different low-caloric sweeteners.
Our overall aim is to measure several distinct MR parameters at 0.064 Tesla, and to use these to derive optimal MRI-protocols in terms of contrast and SNR. Some of these new developments may subsequently be used in clinical research protocols (which…
The general aim for this project would be to understand the neurodevelopmental differences with respect to implicit and explicit forms of threat regulation, by focusing on brain development, sex-steroid hormones and social sensitivity in adolescents…
The primary objective of the second part of the study, which is the focus of this application, is to perform a comparative analysis of the cognitive profile and MRI outcomes of DMD/BMD patients.