352 results
The proposed project focuses on: a) implementation of an improved, standardized method for performing quantitative nailfold capillaroscopy to visualize morphological patterns and evaluate its diagnostic use in patients with (possible) CTD and…
Is SV2A expression in surgically removed tumour and tumour-surrounding tissue of glioma patients suffering from epilepsy correlated with their clinical response to levetiracetam?
Primary objective:To determine the most important risk factors for falls in elderly people with mental retardation and to describe which of these factors may be modified by intervention/treatment, in order to prevent falls.Secondary objective:To…
The present study will focus on the consequences of long-term delay of puberty induced by treatment with Decapeptyl-CR. We will investigate the effects of this treatment in regard to brain functioning, brain development, various endocrine, metabolic…
the study aims to answer the following question:are components of innate immunity in general, and the complementsystem in particular, correlated with and usefull as predictors for the occurrence of macro- and/or microvascular complications in a high…
The study objectives are:1. Getting insight into the biological origin of the typical serum protein profile in breast cancer by comparing the protein profiles in breast tissue of benign breast disease patients and primary breast cancer patients with…
The general objective of this study is to elucidate the cellular components for HIV-1 infection in children.
In the present study we aim to identify the genetic modifiers in this family which underlie differences in severity and type of phenotype by means of linkage analysis.
Using pedigree research in two CVID-families to find clues for genetic testing.
The aim is to gain basic dynamic information for an upcoming accuracy studies whereby the diagnostic value of 4D-RX will be determined. By comparing healthy individuals with those with scapholunate ligament dissociation we expect to detect abnormal…
The aim of the research is to enroll 100 consecutive untreated periodontitis patients for the normal standard treatment. We will investigate by means of venous blood analyses before treatment and 3, 6, and 12 months after treatement whether plasma…
Investigate effect of IF on insulin resistance and possible role acylcarinitin profiles and glycolipids
To evaluate whether an increase in inflammatory- and coagulation parameters can be found in healthy volunteers with elevated hsCRP levels compared to age and BMI matched healthy volunteers with normal hsCRP levels
The objective of this research is to identify genetic host factors influencing the clinical course and treatment of HIV infection. The identification of these genes may lead to new therapeutic or preventive approaches. In addition, the…
To compare the rapidity of onset and the extent of oxidative stress lowering of atorvastatin with that of an (in terms of LDL lowering) equipotent dosage of simvastatin.
Objectives in this study areBto investigate:1a.) the presence and distribution of fasciculations of muscle in Amyotrofic Lateral Sclerosis patients1b.) whether muscle elastography can be used as an early diagnostic tool in Amyotrofic Lateral…
To clearify the etiology of CTS and prognostic factors for the development of CTS.
To determine, by measuring cIMT's, whether the abnormal lipid profile of GD I carriers and patients is associated with atherosclerosis and an increased risk of CAD.
1. The central hypothesis of this study is that genetic polymorphisms in drug metabolising enzymes and regulators of enzyme expression may predispose to ATDH. We propose to evaluate the presence of genetic polymorphisms among TB patients in…
To assess the normal nasal microcirculation in vivo. Also, this research may lead to a better understanding of the pathophysological mechanisms operative in nasal dysfunction. It may help us to differentiate between aetiology of different disorders…