6380 results
The primary objective is to explore the effect on Donning and Doffing of REACTION and their subsystems (ABLE REGAIN and GABLE CORE) in individuals with neurological disorders. The secondary goals include: 1. To explore the effect of REACTION and…
The objective of this study is to investigate the role of platelets in fibrosis and inflammation by examining their effects on key cellular processes. Specifically, we aim to:1. Determine whether activated platelet stimulation induces fibrosis…
Our primary objective is to collect normative reference values in typically healthy developing children, aged 0 - 18 years, for EEG in combination with ERP and eyetracking, and OCT measurements (For details see also paragraph 5.1).
The aim of this study is to determine whether this smart wristband can actually support patients and their parents in managing the consequences of hypothalamic dysfunction. We will investigate what kind of support patients, parents, or caregivers…
Objective 1: The LifeMeds cohort aims to longitudinally identify characteristics of individuals with multimorbidity (at least two of the following chronic diseases: CVD, CRDs,T2DM and/or cancer), including lifestyle behavior and its determinants. 1a…
The overarching objectives of this proposal are: 1) To evaluate the effect of noradrenergic modulation on type I potentials in wakefulness (vertex potentials), and NREM sleep (vertex sharp waves, K-complexes) and on dreaming in NREM sleep; 2) To…
We want to identify which patients will develop arthritis with the long-term and ambitious aim of trying to prevent the development of arthritis before it occurs. As many (most) participants will not develop arthritis, we are also studying the…
The goal of the current study is to evaluate both the feasibility and validity of the Corival ALT prototype for exercise testing in patients with lower limb deficits.
To investigate the effect of multiple sessions of whole body NMES, with or without consecutive protein intake, on muscle protein synthesis.
Primary Objective: To determine how exposure to +5Gz forces affects small airway function when breathing ambient air (21% oxygen) and oxygen enriched air (60% oxygen) , without the breathing component of the AGSMSecondary Objective: To explore the…
Primary objective: To assess the feasibility of donor screening, collection, production and storage of sufficient CB-RBC products to potentially meet the transfusion need in extremely preterm neonates.
The overall aim of the Ageinglines cohort study is to better understand the biological ageing process and its association with the onset (pre)frailty and well-being in later life and to identify targets for delaying the biological ageing process…
The REPLACE study aims to determine whether not changing the catheter (catheter retained) for catheter-associated urinary tract infections (CAUTI)affects the recurrence-risk of CAUTI.
This is a pilot study for investigating the cause of recurring cerebral thrombo-embolic events in a patient after (branched) TEVAR surgery. The main aim of this logistical pilot is to develop a workflow for investigating blood flow patterns in such…
Primary objective is to investigate if the sEMG signal derived from the SERA device has an association with weaning failure, defined as an unsuccessful SBT, or extubation failure, defined as the need for re-intubation for respiratory reasons within…
The general objective is to validate a new non-invasive retinal imaging tool that allows the identification of relevant biomarkers in the retina in degenerative diseases of the brain and the eye by scattering and absorption properties.
Optimization of OE-MRI protocols and workflows to prepare for hypoxia mapping and quantification on an MR-linac
The objective is to initiate a hiPSC-resource from 10 genotyped participants of the Doetinchem Cohort Study, with a characterized life course history of up to 35 years during their adult life, with the intent to deploy mechanistic and causality…
Primary RQ: 1) Is time spent in daylight associated with better mood in recently remitted depression patients? Secondary RQ*s: 2) Is the association dependent on age, sex, circadian rhythms and chronotype? 3) Is the association dependent on timing…
We have preliminary data from blood collected in other studies that indeed measuring blood microbiomes is more informative as sampling the corresponding faeces samples and we have built a bio-informatical pipeline that apparently allows its analysis…