493 results
In this study the efficacy of a novel monoclonal antibody on the development of psoriasis in the humanized mouse model will be investigated.This experimental compound will be compared with 2 registered drugs, i.e. Humira en Stelara.
The main objective of the study is to monitor the factors effecting success of PDT, namely oxygen, photosensitizer concentration and, light dose before and during illumination to gather data that can be clinically correlated and later implemented.
The main objective of this project is to examine the neural correlates of the motivation to be moral in group contexts. We will address three related issues: how the desire to be seen as moral affects people*s self-views and motivation to display…
Research GoalsUsing cross-sectional data we will test whether control and affective brain regions follow different developmental time courses. The first study will focus on the development of inhibitory control (stimulus-driven and intentional),…
The aim of this study is to determine whether the hydration status influences the RNFL thickness.
- To correlate clinical and biochemical cardiovascular risk factors to arterial wall 18-FDG uptake in large artery atherosclerotic lesions.- To correlate inflammatory markers to arterial wall 18-FDG uptake in large artery atherosclerotic lesions.
The principle aim of this study is to characterise all of the genetic alterations that are present in different types of breastcancer by comparing the cancer genome to it's matched normal genome.The primary goals of this ICGC project, which…
Collecting T cells of 2 stage IV melanoma patients via leucapheresis for conducting test runs in order to develop a gene therapy study.
The key objectives of this study is to examine i) the neural correlates of social interactions with peers, ii) to examine the development of these neural patterns across adolescence, and iii) to focus on their links with psychosocial adjustment.
Examine how unexpected reward and unexpected punishment affect working memory, that is, the ability to maintain information across time, update task-relevant information and ignore task-irrelevant information.Determine the extent to which…
The aims of this study are: 1. To investigate the difference in body composition, fat distribution, energy expenditure, substrate and dietary fat oxidation in Asians and Caucasians. 2. To investigate the effect of overfeeding a high fat diet on…
Objectives are: A. to assess the incidence of ABI in children and youth (up to 25 years of age). B. to describe the consequences of ABI, restrictions in participation and health care needs 2 years post-onset, as well as associated factors.
Determine arm and shoulder function and quality of life scores before and after treatment of SST. The untreated extremity can serve as a control.Determine riskfactors for a poor functionale outcome and quality of life after treatment for SST (e.g.…
This pilot study will enable us to assess critical sample points in time to be able to draw a reliable curve of the concentration of various parameters that play a role in iron kinetics. This is essential for the planning of future research into the…
The goal of this research project is to develop a multidisciplinary guideline for the responsible and restrictive treatment of freedom restriction in the care for elderly with dementia and people with intellectual disabilities. In this guideline the…
Within this complete European consortium animal models as well as patient material are utilized, in order to uncover the pathogenic pathways in OPMD that are at the centre of the disease, eventually in order to design rational evidence based…
To determine the reproducibility and responsiveness of the Scapula Position Test and the WORC, WOSI and WOOS questionnaires in patients with shoulder symptoms.
The primary objective of this study is to understand the neurocognitive basis of conflict and reward processing and their interactions. To this end, we will acquire fMRI data and behavioral responses of 25 healthy female adults (aged 18-30 years).
zie bovenstaand
Can clinical experience be related to activation differences using fMRI? On the basis of previous studies by Schmidt cs. (Erasmus University Rotterdam and one of the investigators in the present study) it has been demonstrated that clinical…