50 results
Mainstreaming of germline genetic tests in regular healthcare is feasible for healthcare professionals and acceptable for both patients and healthcare professionals
Most patients undergoing spine surgery with pedicle screw instrumentation will experience insufficient pain relief in the first three days after surgery, whereafter postoperative pain can be managed with conventional, non-opioid analgesics in most…
The test product supports normal physical growth in healthy term infants
"The main objective of this trial is to assess long-term performance and obtain real-world experience with the bi-hormonal fully closed loop system (Inreda AP®)"
To determine: 1) How neuropsychiatrich problems change over time during the first year after stroke; 2) Which determinants are related to the course of neuropsychiatric problems over time during the first year after stroke; 3) What are the…
Primary Objective: Does DBS result in cognitive changes in patients with OCD on the long term? Secondary Objective(s): Does DBS result in personality changes in patients with OCD on the long term?Are certain cognitive profiles associated with…
To investigate the effect of whey and casein ratio of IFT on intragastric behavior, gastric emptying and postprandial plasma metabolome
To assess whether co-ingesting keto-analogues of branched-chain AAs along with protein during HD can attenuate HD-initiated muscle catabolism.
Primary Objective: To quantify the variation in post-prandial plasma AA profiles between (and within) individuals after consumption of a poorly digestible plant protein source (lucerne). Secondary Objective: To compare the variation in postprandial…
To assess the impact of protein in a solid (bar) and liquid (drink) form on post-prandial amino acid responses in vivo in healthy young women.
The primary objective is to determine if there is a difference in autonomic function between patients with Alzheimer*s disease (MCI and AD) and a matched control group. The secondary objectives will be explorative and aimed to investigate…
The objective of this exploratory trial is to explore the acute and chronic effects of daily olive leaf extract supplementation on muscle energy and fatigue in healthy male adults
To study the effect of individual control of the light on thermal comfort
To contribute to the evaluation of 'fasting mimicking diet' application in oncotherapeutic setting and to gain insight on the underlying mechanisms in response to a fasting mimicking diet. This explorative study focuses on the immune…
To examine the thermophysiological responses to prolonged exercise in hot and humid environmental conditions in patients with a history of exertional heat stroke or malignant hyperthermia susceptibility and compare the thermophysiological responses…
The objective of this proof-of-concept study is to investigate (differences in) small intestine microbiota and postprandial glycemic responses.
Obtain phased-contrast 4D flow MRI scans in 20 healthy volunteers to quantify local blood flow in the thoracic and abdominal aorta and extract boundary conditions for future in vitro studies. Furthermore, the 3D geometry of the vessels within…
To compare the post-prandial muscle protein synthetic response following ingestion of a whole-food meal containing meat versus the ingestion of a meal containing only plant-based protein sources in vivo in healthy, older men and women.
We here validate the algorithms for movement analysis that were developed previously in healthy participants (METc 2019.542; regarding quantitative aspects of movement) and that were derived from a review of the literature (regarding qualitative…
Primary Objectives* To investigate the intra-variability (day-to-day) of glucocerebrosidase pathway biomarkers in HV, PD-GBA+ and PD-GBA-Secondary Objectives* To investigate the intra-variability (within-day) of glucocerebrosidase pathway biomarkers…