110 results
The present study will focus on the consequences of long-term delay of puberty induced by treatment with Decapeptyl-CR. We will investigate the effects of this treatment in regard to brain functioning, brain development, various endocrine, metabolic…
The aim of this experimental study is to find out whether children and young adults with the DS have an altered pain sensitivity in comparison with children and young adults without cognitive impairement.
1) To examine whether adolescents with depression, show abnormalities during specific attentional processes, compared to normal controls, 2) To determine whether abnormalities in attentional processes can be considered as prognostic markers of a…
To identify novel childhood cancer-predisposing genes in children.
Purpose: is there a rotational disability after Prevotnailing of forearm fractures in children and is this caused by a bony deficit.
To investigate the onset and short term natural course of ADD and TMJ hypermobility in children, and to give insight into some related risk factors.
The goal of this study is to determine whether a short course of amoxicillin/clavulanic acid reduces the number of urinary tract infections in children that have been catheterized during a short period.
The objective of the study is to determine what the clinical value is of measuring GE of liquids in 50 SMID children. The primary study parameter is how often DGE of liquids occurs in this study group. Secondary study parameters include…
The aim of the study is to archive an objective measure for auditory processing disorders, using the P300 measurement, an auditory event related potential. This to be able to discriminate between children with and without auditory processing…
Primary Objective: To investigate the effect of treatment with nebulized rhDNase targeted to the peripheral airways compared to rhDNase targeted to the central airways on FEF75 in children with CF who are on maintenance treatment with rhDNase.…
Aim of the study is to develop and test a brief intervention for adolescents who have to be treated in the emergency department of a hospital due to excessive alcohol use.
The objective of this study is to identify determinants, to determine the transmissibility and to determine the burden of disease of NT-MRSA and CA-MRSA carriage compared to other typeable MRSA strains in the community.
The main objectives of this study are to describe behavioural problems in children aged 0 to 4 years and posttraumatic stress symptoms in children aged 8 to 17 years and to study the course and determinants of these problems. Further, this study…
The aim of this project is to collect new normative data for the Dutch children, for both parts of the M-ABC2. The opportunity will also be taken to extend the age range of the test down to 3 years and up to 16 years. Also the reliability and the…
In patients who have undergone surgical repair of TOF, we aim to- assess the development of RV dimensions and function in relation to clinical outcome, in a time dependent manner,- identify, chracterize and quantify markers in blood samples, using…
The purpose of this study is to improve, implement and evaluate an intervention program to improve physical activity in daily life and sportsparticipation of adolescents and young adults with MMC. The purpose of the intervention "Active…
The purpose of this investigation is identify thecausative oncogenes in 17p11.2-p12, to clarify the mechanism of their amplification, and to determine their diagnostic and prognostic importance for patients with osteosarcoma.
To determine the feasibility of a trainingprogram in childhood cancer survivors in the primary health care system
The objective of this extension study is to assess the long-term safety and efficacy of Myozyme treatment in patients with Late-Onset Pompe Disease who were previously treated under the placebo-controlled, double-blind study AGLU02704.