228 results
Accelerometers are already widely used in research in chronic diseases, but also increasingly used by health professionals in general practice. It is however not known in occupational therapy, if these measurements are feasible. Furthermore, no…
We hypothesize that storytelling (in the form of a sub-plot), concerning the effects of (un)healthy lifestyle on heart risk, in a popular Dutch TV show for children can cause sustainable positive lifestyle change. Furthermore, we hypothesize that…
HbA1c is still considered to be the most reliable indicator of the average blood glucose concentration over a longer period of time and therefore used as a guide for treatment of patients with diabetes mellitus (DM). But, HbA1c levels are influenced…
Short-term (1-year) results of renal transplantation are now excellent (over 95%). Long-term (10-year and longer) results are, however, still disappointing. Where most research has focused on immunosuppression and infections, we hypothesize that due…
Deep neuromuscular block has advantages over a moderate neuromuscular block in term of outcome (pain, respiration) but has otherwise no effects on the patient
Body weight has an effect at the trough concentrations of DOACs in patients.
More than in any other field, the nature of healthcare, makes that the consequences of human error can take an immense size. Increasingly, people state that complaints and claims in healthcare increase and accrue. Nevertheless, recent research into…
We hypothesize that 18F-FDG is a valide marker for metabolic activity in adipose tissue and even more pronounced in type 2 diabetes.
This is an exploratory study to further delineate the microenvironment of the PT and (S)LNs in cervical cancer.
We hypothesize that patients with craniopharyngioma and hypothalamic obesity have less efficacy of bariatric surgery compared to controls from a 'general' obese population
Prior studies have shown reagent dependent differences in sensitivity to circulating clotting factor VII (FVII). This reagent dependent sensitivity to FVII can explain the INR differences between laboratory methods and point-of care devices found in…
It will be investigated whether passive leg raising and stroke volume variations can be used in predicting renal responses to fluid administration. Our hypothesis is that dynamic predictors of cardiac fluid responsiveness can predict an increase in…
Low-molecular-weight heparins (LMWHs) are frequently used in the prophylaxis and therapy of venous thromboembolism (VTE) and the prophylaxis of arterial thromboembolism. LMWHs are mainly excreted by the kidneys and may accumulate in patients with…
Youth at intermediate vocational education (ROC's) show excessive alcohol and drug use, which can have various detrimental consequences. For this vulnerable group of youngsters a targeted, multicomponent plan of attack was developed in…
a. Ascorbic acid in combination with metformin (500mg BD) improve the glucose tolerance with a daily dose of 500mg over a period of 12 months. b. Ascorbic acid with metformin reduce the adverse effects/events. c. Acetylesalicylic acid in…
To determine the role of 5-HT2 and 5-HT1A receptors in learning and memory. It is expected that: 1. An acute dose of MDMA will produce impairments on laboratory measures of learning and memory; 2. MDMA-induced memory impairment will be reversed…
A reduced peritoneal exposure to glucose and thereby to glucose degradation products will influence the incidence and severity of peritonitis and may modify peritoneal membrane characteristics.
Hypothesis A: We expect a decline in measured musclemass during the initial days of hospital admission, also we do not expect hydrational changes to be of great influence on estimated muscle mass. Hypothesis B: We expect that the time of the day on…