3434 results
A real world registry to compare dual therapy with Dabigatran/Clopidogrel to Usual care (Triple Therapy) with Dabigatran/Clopidogrel/Aspirin in patients with an indication for NOAC undergoing PCI in the setting of ACS. Hypothesis: Dual therapy with…
To investigate if currently employed ultrasound measurements for diagnosing a portal vein anastomosis stenosis remain reliable when children are not fasting
The primary objective is to assess the long-term (5-8 years) quality of life in patients who previously participated in the placebo-controlled randomized controlled trial on the effect of prolonged antibiotic treatment on persistent symptoms…
To assess the patient level CDR and region level PPV of rhPSMA-7.3 (18F) PET for BCR of PCa using histopathology or imaging as a SoT. Secondary Objectives: 1. To assess the patient level CDR and region level PPV of rhPSMA-7.3 (18F) PET in the…
The primary objective is to investigate gastro-intestinal complaints during 18 day Fermotein consumption. Secondary objectives are to assess blood based parameters related to general health. Outcomes will be part of a novel food dossier.
The aim of this study is to investigate the combined and independent roles of the two major stress hormones, noradrenaline (NA) and cortisol, in intentional forgetting under stress using a pharmacological manipulation. As such, our aim is to…
The goal of this study is to gain insight into the mechanisms underlying the relation between consumption speed and satiation. This study related chewing duration (short/long) for standard lunches to blood glucose levels in 3 post-lunch hours. Also…
The purpose of this study is to investigate how quickly and to what extent PF-06826647 is absorbed and eliminated from the body (pharmacokinetics). PF-06826647 will be labelled with Carbon-14 (14C) and can be traced in blood, urine, and feces.This…
The primary objective is to assess, in healthy subjects with a body mass index (BMI) greater than or equal to 25.0 kg/m2, the injection site pain experience of 9 excipient solutions (Trial Products 4 to 12), intended to be used in future…
The identification of a new gene(s) that causes autosomal dominant polycystic liver disease.
The primary objective is to evaluate the feasibility of FDG-PET/MRI to improve tumor response assessment after nCRT compared to standard FDG-PET/CT.
The main goal of this study is to analyse the influence of the menstrual cycle on NK cell receptor variability.
To assess whether a complete pathological respons (cPR) after neo-adjuvant chemotherapy can be predicted based on clinical, radiological, and histological variables and on a wide set of tissue and blood/urine (liquid biopsy) biomarkers (DNA/RNA).…
The primary objective is to determine the effect of ICU-VR at three months after discharge on psychological sequelae and HRQoL up to 6 months after discharge in patients treated for COVID-19 on the ICU. The secondary objective is to determine the…
The primary objective is to test the feasibility of EGP quantification in adult GSDIa patients by stable isotopes after a single oral D-[6,6-2H2]glucose dose. Secondary objectives are to compare EGP assessed by a single oral D-[6,6-2H2]glucose dose…
The primary objective is to achieve intraoperative detection of histologically or cytologically proven GIST and metastases with ICG and NIR fluorescence imaging. The primary end-point is the diagnostic value of ICG in detecting GIST with NIR…
To investigate whether timely delivery of CBT, i.e. 3 to 6 months after COVID-19 diagnosis or hospital discharge, will lead to a significant relevant reduction in fatigue severity (primary outcome), will lead to a clinically relevant reduction in…
Primary objectiveTo compare the event free survival per pathological review committee (PRC) of nivolumab plus BCG vs BCG alone in all randomized ParticipantsEFS, defined as the time from randomization until any of the following events: recurrence (…
This study has been transitioned to CTIS with ID 2023-509675-16-01 check the CTIS register for the current data. Our objective is to study if reduced anticoagulation targets diminish bleeding complications without an increase in thromboembolic…
As an extension on a study that is currently running and has previously been approved by the METC (NL69407.091.19) the aim of this study is to identify the importance of scene context in the perception of objects by manipulating activity in object…