80 resultaten
Doel van het onderzoek is om bij gezonde mannelijke vrijwilligers het effect van vasten en vetrijke voeding te bestuderen op het metabolisme van paracetamol.
Belangrijkste doel van de studie is de optimale belichtingshoek en intensiteit bepalen voor het opwekken van niet-visuele responsies met behulp van blauwe LED verlichting in een bril.
Het vaststellen van veranderingen in de kerntemperatuur onder remming van de PGE2 productie onder simultane blokkade van COX op centraal en perifeer niveau (paracetamol + ibuprofen) vergeleken met een controleconditie en met blokkade van COX op…
Primary objective: To determine the safety of once daily inhalation of the recommended daily dose of tobramycin with the Akita® and the PARI-LC® Plus nebulizer in patients with CF. Systemic absorption can be used as surrogate parameter for safety.…
We hypothesize that inhalation of helium gas induces release of protective factors in the blood, which can be used to protect different cell types against ischemia/reperfusion injury.
With a daily activity programme concerning activities of daily life with occupational therapy by volunteers , physiotherapy and ergotherapy , probably functional decline does not develop or the condition of the patients can improve and it can reduce…
Both hypoxia and hyperoxia can lead to organ damage in preterm infants. For this reason the transcutaneously measured oxygen saturation (SpO2) is kept within a range between 86% and 95%. Hypoxia is mainly caused by immature or impaired control of…
High-output enterocutaneous fistula (>500ml/day) or high-output enterostomy (>1500 ml/day) are associated with a number of complications such as dehydration, malnutrition psychological and wound care problems. Lanreotide inhibits the…
Cytokine production differs when subjects ly on the rigid spineboard compared to the soft-layered spineboard.
The primary objective of this study is to obtain clinical proof of principle that the Addition of a PgP/BCRP inhibitor increases CNS concentrations of tyrosine kinase inhibitors by inhibition of drug efflux transporter function in the blood brain…
Part 1: Quantification of individual patient-prosthesis interactions - Determination of the instantaneous effect of prosthetic knees with variable biomechanical properties on the gait pattern of persons with an upper leg amputation (Part Ia). -…
We hypothesize that the Vanguard TKA show similar and comparable outcome measures and survival as the Maxim TKA
Allogeneic blood transfusions are reduced when comparing the use of an ABT system to no use of post-operative drains in patients who underwent TKA.
The hypothesis of this study is that dosing everolimus 5mg twice daily(BID) instead of 10 mg once daily (QD) decreases the incidence of side effects, as a result of a lower Cmax while maintaining Cmin and AUC.
We will investigate the effects of high dairy intake on metabolic flexibility, glucose metabolism and insulin sensitivity, which are all important characteristics of (metabolic) health. We hypothesize that high dairy intake improves insulin…
In this study we will investigate whether the effects of physical activity on cognitive performance are present after short (10 minutes), medium (20 minutes) or longer (30 minutes) bouts of moderate exercise in order to establish the feasibility of…
Objective: To assess the diuretic effect of three standard glasses of beer, red wine and spirits in euhydrated elderly men.
The primary objective of this study is to validate MRI as a functional measuring device for directly monitoring gastric emptying in vivo
We hypothesize that there is no difference between the Day Care surgery pathway compared to the Rapid Recovery pathway in patients operated for unicompartmental knee arthroplasty (UKA).