20 resultaten
To determine the influence of the fatty beverage Cow’s milk on the systemic exposure (AUC) to erlotinib in patients with or without concomitant use of a PPI.
To evaluate the effects of a versatile web-based health game on cognition and compliance in Parkinson’s disease with mild cognitive impairment.
With a recently developed Ara h6 ELISA we would like to show the effect of exercise on circulating Ara h6 after peanut consumption
To determine the influence of prednisone on docetaxel pharmacokinetics compared to docetaxel alone
Consumption of foods containing L-arabinose will improve glycaemic and insulinemic response.
Environmental disturbances during ICU submission may explain observed EEG-arousals
The primary objective is to determine whether JWH-018 can be safely administered in healthy volunteers in doses up to 3 mg. Therefore participants will be continuously monitored by a medical doctor and vital signs, laboratory clinical safety and…
Wheelchair mobility skills training and wheelchair fitness training will both increase the level of physical activity in wheelchair using children and adolescents. Wheelchair fitness training prior to wheelchair mobility skills training will show a…
Are hemodynamic values obtained by the non invasive hemodynamic measuring device TL-400 comparable with the values obtained by the standard invasive hemodynamic measuring devices (transpulmonary thermodilution (TPTD) (PiCCO system; Pulsion Medical…
To determine whether 4-FA can be safely administered in healthy volunteers in doses up to 150 mg
The aim of the study is to investigate if a schema mode treatment with cognitive-behavioral, and experiential interventions will be effective for adult patients with autism spectrum disorder (ASD) and at least one personality disorder (PD). The…
Rear-view assistance and obstacle detection are well accepted by older cyclists and support a more safe cycling behaviour
It is expected that PROMISE leads to more enthusaistic natal care professionals for helping preganant women quit smoking and for discussing strategies for smoking cessation more often and that this results in a more effective delivery of stop-…
Protein metabolism consists of amino acid incorporation and amino acid oxidation. We have developed a breath test which is able to measure the oxidation of ingested 13C-protein. We hypothesize that a diet low in protein before the breath test will…
Capillary malformations (¡®port-wine stains¡¯) are congenital abnormalities of the capillary vessels of the skin, causing a red or purple color. Laser therapy is currently the only widely accepted treatment option, but treatment response is…
The primary objective of this study is to assess the (cost-)effectiveness of antimicrobial stewardship interventions in Dutch acute care hospitals with a special focus on the difference in effect between three methods to measure and feed back…
Currently, the effects of nutrition or specific food components, including those on absorption or metabolism, are mostly studied via parameters in blood samples. To reduce the burden for participants of nutritional intervention studies, there is a…
We hypothesize that a single night of short sleep duration (4 hours), compared to normal sleep duration (8 hours) reduces metabolic flexibility, increases insulin resistance and thereby reduces HPA-reactivity. Furthermore, we hypothesize that a…