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We hypothesize that treatment with a DPP-4 inhibitor will enhance the glucagon response to hypoglycaemia in patients with type 1 diabetes.
To determine the influence of curcumin and piperine on tamoxifen pharmacokinetics.
We hypothesize that vardenafil improves cognition. This will be apparent as increased recall/recognition scores in a verbal and pictorial memory task, as well as percentage correct in a spatial memory paradigm.
Isomaltulose reduces the decline in working memory and attention span in older children. This reduction in decline is also seen when lower amounts of isomaltulose are combined with a mix of minerals and vitamins.
Objective of this study is to assess the sensitivity of performance in a number of widely used tests for measuring driver impairment to the dose-effects of alcohol.
We hypothesize that black tea ingestion (approximately 530 mg tea polyphenols) in healthy middle-aged humans will lead to a larger mean forearm blood flow response to acetylcholine (i.e. endothelium-dependent vasodilation) We hypothesize that black…
High-output enterocutaneous fistula (>500ml/day) or high-output enterostomy (>1500 ml/day) are associated with a number of complications such as dehydration, malnutrition psychological and wound care problems. Lanreotide inhibits the…
Inhalation of rhDNase after airway clearande therapy (ACT) increases the expiratory flow at 25% of the actual forced vital capacity (MEF25) compared to inhalation of rhDNase before ACT.
The CPC-mouthrinse inhibit 15% less of 'de novo' plaqueformation compared to a placebo and hexitine over a period of 3 days in a non-brushing model.
We hypothesize that a single night of short sleep duration (4 hours), compared to normal sleep duration (8 hours) reduces metabolic flexibility, increases insulin resistance and thereby reduces HPA-reactivity. Furthermore, we hypothesize that a…
The quality of taste affects sensory specific satiety. This is shown in both liking and wanting processes.
Evaluation of difference in tolerability and efficacy as measured by bonemarkers between generic versus brand alendronate in postmenopausal women with osteoporosis.
Preceding dwell with icodextrin does not influence the results of the 3.86% glucose PET in CAPD.
Co-ingesting keto-analogues of branched-chain AAs along with protein during HD attenuates HD-initiated muscle catabolism.
Administration of a lipid emulsion consisting of long-chain triglycerides (LCT-trial) in non-trained individuals, will induce insulin resistance due to increased DAG accumulation and subsequent activation of the PKC pathway in skeletal muscle.…
Deep brain stimulation of the nucleus accumbens decreases drug use and craving in treatment refractory heroin and/or cocaine dependence.
The aim of this phase I study is to assess the extent of intestinal absorption of rivaroxaban and dabigatran etexilate in adult patients with short bowel syndrome requiring long-term TPN.
Administration of Ibopamine hydrochloride eye drops restores intraocular pressure in patients with hypotony following vitreoretinal surgery or uveitis.
With personal control system, people feel more comfortable.
Long-chain triglyceride (LCT) emulsions with very small droplet sizes (fine emulsion) will lead to enhanced postprandial satiety and reduced energy intake in a subsequent meal, as compared to LCT emulsions with relatively large droplet sizes (coarse…