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Tumor response from erlotinib and bevacizumab as first line treatment in advanced NSCLC will result in “non-progressive disease” within 6 weeks in more than 50% of patients.
It has been hypothesised that, because participatory ergonomics (PE) implementation strategies intervene at all phases of behavioural change for the various stakeholders, they may be successful in increasing the use of ergonomic measures at…
The use of modern antidepressants during pregnancy is associated with changes in fetal movement and development and can lead to seroius withdrawal syndromes after birth. Antidepressant use as well as discontinuation of medication during pregnancy…
1. Comprehensive geriatric assessment has no benefits in selecting patients fit for chemotherapeutic treatment, compared to clinical judgement by the medical oncologist; 2. Observational report of the functional outcome of treating ovarian carcinoma…
Clients in a consumer-driven program for recovery, empowerment and experiential expertise will have better outcomes on self-efficacy and empowerment than clients on a waiting list for the program.
There are predictive markers of treatment response (or non-response) at baseline or during early beginning of treatment?
The helical geometry of this vascular access prosthesis reduces flow stagnation and low shear stress at the venous anastomosis resulting in diminished neointimal hyperplasia.
In patients presenting with chest pain complaints and an intermediate risk of coronary artery disease, Multi-Slice Computed Tomography (MSCT) will have a higher specificity as compared to myocardial perfusion imaging (MPI). Accordingly, MSCT may…
The hypothesis will be tested that early luteal phase administration of high dosages of Estradiol and/or Progesterone in normo-ovulatory volunteers will reduce the luteal phase length.
One tailored letter on smoking cessation will lead to more quit attempts at follow-up.
Botulinum toxin A declines the severity of tardive dyskinisias.
anatomy sparing 2-incision total hip arthroplasty (THA) has a better functional outcome than conventional THA.
Concurrent chemoradiation is superior to sequential chemoradiation.
There are two research questions: 1. Does cognitive behavioural therapy (CBT) in groups lead to a significant decrease of fatigue and functional impairment of CFS patients compared to a waiting list condition? 2. For which patient is group therapy a…
Oral 6-thioguanine (6TG) results in a high intrahepatic exposure to 6TG generated metabolites.
The two tested interventions (Good Behavior Game and parent management training) will cause a decrease in aggression, victimization, disruptive behavior, anxiety and depression in elementary school children.
1. When patients visit their GPs with unexplained complaints it is cost effective to follow a watchful waiting strategy of four weeks before ordering laboratory tests; 2. A systematically developed quality improvement strategy, based on barriers…
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An upfront RBCT aiming at low-normal Hb levels will ameliorate anemia-caused tumor hypoxia-related resistance to chemotherapy before the start of chemotherapy and may decrease secondary anemia-induced endogenous release of cytokines like VEGF,…