161 resultaten
Covered self-expandable metal stents for benign biliary strictures: a prospective multicenter trial.
Benign biliary strictures occur most frequently after surgical procedures, chronic pancreatitis or iatrogenic ampullary stenosis. Traditionally, surgery has been the treatment of choice. A less invasive alternative is endoscopic or percutaneous…
PHASE 1: 1. Identify the extent to which care management (as a competency) is implemented in the curriculum of postgraduate medical education in the Netherlands; 2. Evaluate stakeholders’ perceptions of the concept of care management (in medical…
In this observational trial we would like to study the possible correlation between the probe-drug dextromethrophan and tamoxifen pharmacokinetics. In case a good correlation is available, this might help in a stepwise development of truly…
The novel anti–tumor necrosis factor monoclonal antibody adalimumab was significantly superior to placebo for long-term treatment of CD irrespective of concomitant immunosuppressive therapies, including the thiopurines azathioprine (AZA) and 6-…
DYANA Study - Dynamic Annuloplasty System with Activation for the Treatment of Mitral Regurgitation.
To assess the safety and efficacy of the MiCardia Dynamic Annuloplasty System for the treatment of mitral regurgitation with optional intraoperative activation and optimization.
To assess the current patterns of surgical or instrumental treatment and indications for RCC treatment.
There is some evidence pointing towards a risk liposoluble vitamin deficiency in patients receiving long-term octreotide treatment. This is becoming clear only recently as there are now patients using this drug since it became available. Groups…
Test the hypothesis that a divisional calculation of heat loss, and incorporation of skin temperature of the extremities during mild cold exposure will indicate an age effect on heat loss between young and elderly. An additional purpose is to test…
Improved detection of tumor.
A slow and unpredictable deterioration of the capabilities of the older patient can lead to a vulnerable situation, often unnoticed by the caregiver. As a consequence, care is delayed and acute problems will arise that will need an immediate…
Het is veilig en haalbaar om in 1-2 gastroscopieen zowel een BDstent te plaatsen als brachytherapie toe te dienen.
Our overall aim is to create a cost effective non-invasive method of pre-surgical assessment of language and memory function using MEG scanning. We propose a research project with the key objective to evaluate the effectiveness of a Dutch…
Multi-modality imaging can predict repsonse to systemic treatment in colorectal cancer.
Conservative conservative treatment of displaced wrist fractures with a cast in which the wrist is 20 degrees dorsiflexed is better than a neutral position in terms of re-dislocation and functional outcome.
1. To evaluate the clinical performance of MET PET during rhTSH stimulation and to compare the results of the rhTSH stimulated MET PET with the standard rhTSH stimulated FDG PET in patients with negative post-treatment 131-I scans and elevated serum…
It can be expected that the during the tasks with resistance, the movements are performed slower, less smooth and with less movement range. Also a larger amplitude in muscle activation can be expected. During the tasks with gravity compensation,…
The new developed brace gives better correction by higher body brace interface pressures than the gold standard Boston brace.
Clinimetric properties of questionnaire in an observational study.
By detection of disease specific deviations in emotion processing in unipolar vs bipolar patients, affective neuropsychological tests and fMRI could be used to discriminate between both affective disorders.