80 resultaten
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The aim of this study is to validate the Dutch versions of the PainDETECT questionnaire PD-Q and the ‘Douleur neuropathique en 4 questions’ (DN4) for use in primary and specialist medical care settings for patients with LBP and NSP and patients with…
The depression prevention program ("Op Volle Kracht") will be delivered by teachers in the school curriculum in schools with adolescents from high-risk background. It is expected that adolescents who receive the interventions will show…
Good oocyte quality and maturity are important prerequisites for higher fertilization and implantation rates in IVF/ICSI treatment cycles. Reactive oxygen species (ROS) are produced within ovarian follicles, especially during ovulation process, and…
Antireflux surgery is one of the most common major operations performed in pediatric patients. Most studies on the outcome of antireflux surgery in children are limited to retrospective data, case reports or are based solely on symptoms. A…
we hypothesize that there is a link between gut microbiota composition and development of venous thrombosis.
Oral pazopanib once daily is safe and effective in advanced endometrial cancer for which no other therapies are available.
Preoperative biliary drainage with metal stent in patients with resectable periampullary cancer results in less stent-related and drainage-related complications when compared to preoperative biliary drainage with plastic stents.
Breast cancer is one of the most common forms of female cancer worldwide. There are major limitations to the current imaging techniques that are used for diagnosing breast cancer. There is no single technique that combines an excellent sensitivity…
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Depression is a major health problem in glioma patients, with emotional, cognitive and physical sequelae. Depression in these patients may be associated with increased morbidity and even with poorer survival. In addition, depression is the most…
The hypothesis to be tested is the relationship between the number of blood transfusions, serum ferritin and transferrin saturation level and MRI T2*Heart, T2*Liver.
The current study evaluates whether accurate optical diagnosis of small colorectal polyps (<10mm) in vivo in a non-expert setting can be achieved, resulting in the omission of formal histopathology, which could make colonoscopy more efficient…
This study will test the hypothesis that acute preoperative administration of statins will offer a better protection against MIRI than long term preoperative administration does.
When the optimal MRI protocol for imaging the sacral plexus and its branching nerves is known, the sacral plexus of children having neurogenic bladder dysfunction due to congenital spinal or sacral anomalies can be imaged. Because not much is known…
To prospectively assess the efficacy, feasibility and safety of a systemised endoscopic surveillance protocol in large multicentre HPS cohort.
[11C]laniquidar has favourable brain and plasma kinetics, and also a small intra-subject variation in humans.
Not applicable: Phase 1 study --> Safety and Tolerability of Nebulized Amoxicillin-Clavulanic Acid in Patients with COPD.
The effectiveness of a school-based indicated depression prevention program ('Op Volle Kracht') will be tested in a Dutch sample of adolescent girls with elevated depressive symptoms (aged 12-14 years). It is expected that the adolescent…
The primary objective is to assess the safety of treatment with escalating dosages of VELCADE in combination with ZARNESTRA in subjects with Intermediate-2 or high risk MDS according to the IPSS classification.